Machine Learning Approaches to Predict Chronic Lower Back Pain in People Aged over 50 Years

<i>Background and Objectives</i>: Chronic lower back pain (LBP) is a common clinical disorder. The early identification of patients who will develop chronic LBP would help develop preventive measures and treatment. We aimed to develop machine learning models that can accurately predict t...

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Autores principales: Jae-Geum Shim, Kyoung-Ho Ryu, Eun-Ah Cho, Jin Hee Ahn, Hong Kyoon Kim, Yoon-Ju Lee, Sung Hyun Lee
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Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/18b154ed718a4afda00f4e53d0622d5e
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spelling oai:doaj.org-article:18b154ed718a4afda00f4e53d0622d5e2021-11-25T18:18:47ZMachine Learning Approaches to Predict Chronic Lower Back Pain in People Aged over 50 Years10.3390/medicina571112301648-91441010-660Xhttps://doaj.org/article/18b154ed718a4afda00f4e53d0622d5e2021-11-01T00:00:00Zhttps://www.mdpi.com/1648-9144/57/11/1230https://doaj.org/toc/1010-660Xhttps://doaj.org/toc/1648-9144<i>Background and Objectives</i>: Chronic lower back pain (LBP) is a common clinical disorder. The early identification of patients who will develop chronic LBP would help develop preventive measures and treatment. We aimed to develop machine learning models that can accurately predict the risk of chronic LBP. <i>Materials and Methods</i>: Data from the Sixth Korea National Health and Nutrition Examination Survey conducted in 2014 and 2015 (KNHANES VI-2, 3) were screened for selecting patients with chronic LBP. LBP lasting >30 days in the past 3 months was defined as chronic LBP in the survey. The following classification models with machine learning algorithms were developed and validated to predict chronic LBP: logistic regression (LR), k-nearest neighbors (KNN), naïve Bayes (NB), decision tree (DT), random forest (RF), gradient boosting machine (GBM), support vector machine (SVM), and artificial neural network (ANN). The performance of these models was compared with respect to the area under the receiver operating characteristic curve (AUROC). <i>Results</i>: A total of 6119 patients were analyzed in this study, of which 1394 had LBP. The feature selected data consisted of 13 variables. The LR, KNN, NB, DT, RF, GBM, SVM, and ANN models showed performances (in terms of AUROCs) of 0.656, 0.656, 0.712, 0.671, 0.699, 0.660, 0.707, and 0.716, respectively, with ten-fold cross-validation. <i>Conclusions</i>: In this study, the ANN model was identified as the best machine learning classification model for predicting the occurrence of chronic LBP. Therefore, machine learning could be effectively applied in the identification of populations at high risk of chronic LBP.Jae-Geum ShimKyoung-Ho RyuEun-Ah ChoJin Hee AhnHong Kyoon KimYoon-Ju LeeSung Hyun LeeMDPI AGarticlechronic lower back painmachine learningartificial neural networklogistic regression k-nearest neighborsnaïve Bayesdecision treeMedicine (General)R5-920ENMedicina, Vol 57, Iss 1230, p 1230 (2021)
institution DOAJ
collection DOAJ
language EN
topic chronic lower back pain
machine learning
artificial neural network
logistic regression k-nearest neighbors
naïve Bayes
decision tree
Medicine (General)
R5-920
spellingShingle chronic lower back pain
machine learning
artificial neural network
logistic regression k-nearest neighbors
naïve Bayes
decision tree
Medicine (General)
R5-920
Jae-Geum Shim
Kyoung-Ho Ryu
Eun-Ah Cho
Jin Hee Ahn
Hong Kyoon Kim
Yoon-Ju Lee
Sung Hyun Lee
Machine Learning Approaches to Predict Chronic Lower Back Pain in People Aged over 50 Years
description <i>Background and Objectives</i>: Chronic lower back pain (LBP) is a common clinical disorder. The early identification of patients who will develop chronic LBP would help develop preventive measures and treatment. We aimed to develop machine learning models that can accurately predict the risk of chronic LBP. <i>Materials and Methods</i>: Data from the Sixth Korea National Health and Nutrition Examination Survey conducted in 2014 and 2015 (KNHANES VI-2, 3) were screened for selecting patients with chronic LBP. LBP lasting >30 days in the past 3 months was defined as chronic LBP in the survey. The following classification models with machine learning algorithms were developed and validated to predict chronic LBP: logistic regression (LR), k-nearest neighbors (KNN), naïve Bayes (NB), decision tree (DT), random forest (RF), gradient boosting machine (GBM), support vector machine (SVM), and artificial neural network (ANN). The performance of these models was compared with respect to the area under the receiver operating characteristic curve (AUROC). <i>Results</i>: A total of 6119 patients were analyzed in this study, of which 1394 had LBP. The feature selected data consisted of 13 variables. The LR, KNN, NB, DT, RF, GBM, SVM, and ANN models showed performances (in terms of AUROCs) of 0.656, 0.656, 0.712, 0.671, 0.699, 0.660, 0.707, and 0.716, respectively, with ten-fold cross-validation. <i>Conclusions</i>: In this study, the ANN model was identified as the best machine learning classification model for predicting the occurrence of chronic LBP. Therefore, machine learning could be effectively applied in the identification of populations at high risk of chronic LBP.
format article
author Jae-Geum Shim
Kyoung-Ho Ryu
Eun-Ah Cho
Jin Hee Ahn
Hong Kyoon Kim
Yoon-Ju Lee
Sung Hyun Lee
author_facet Jae-Geum Shim
Kyoung-Ho Ryu
Eun-Ah Cho
Jin Hee Ahn
Hong Kyoon Kim
Yoon-Ju Lee
Sung Hyun Lee
author_sort Jae-Geum Shim
title Machine Learning Approaches to Predict Chronic Lower Back Pain in People Aged over 50 Years
title_short Machine Learning Approaches to Predict Chronic Lower Back Pain in People Aged over 50 Years
title_full Machine Learning Approaches to Predict Chronic Lower Back Pain in People Aged over 50 Years
title_fullStr Machine Learning Approaches to Predict Chronic Lower Back Pain in People Aged over 50 Years
title_full_unstemmed Machine Learning Approaches to Predict Chronic Lower Back Pain in People Aged over 50 Years
title_sort machine learning approaches to predict chronic lower back pain in people aged over 50 years
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/18b154ed718a4afda00f4e53d0622d5e
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