Comparison of bias and resolvability in single-cell and single-transcript methods
Rammohan et al. propose a generalizable framework for performing multiple methods in parallel using split samples, so that experimental variability is defined and compared between methods. Their framework provides a practical solution for benchmarking and comparing the performance of any method, ill...
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Nature Portfolio
2021
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oai:doaj.org-article:18b4195254e744b8911081408a581ce22021-12-02T15:56:49ZComparison of bias and resolvability in single-cell and single-transcript methods10.1038/s42003-021-02138-62399-3642https://doaj.org/article/18b4195254e744b8911081408a581ce22021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02138-6https://doaj.org/toc/2399-3642Rammohan et al. propose a generalizable framework for performing multiple methods in parallel using split samples, so that experimental variability is defined and compared between methods. Their framework provides a practical solution for benchmarking and comparing the performance of any method, illustrated by analysing single-cell and single-transcript methods.Jayan RammohanSteven P. LundNina AlperovichVanya ParalanovElizabeth A. StrychalskiDavid RossNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021) |
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DOAJ |
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EN |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Jayan Rammohan Steven P. Lund Nina Alperovich Vanya Paralanov Elizabeth A. Strychalski David Ross Comparison of bias and resolvability in single-cell and single-transcript methods |
description |
Rammohan et al. propose a generalizable framework for performing multiple methods in parallel using split samples, so that experimental variability is defined and compared between methods. Their framework provides a practical solution for benchmarking and comparing the performance of any method, illustrated by analysing single-cell and single-transcript methods. |
format |
article |
author |
Jayan Rammohan Steven P. Lund Nina Alperovich Vanya Paralanov Elizabeth A. Strychalski David Ross |
author_facet |
Jayan Rammohan Steven P. Lund Nina Alperovich Vanya Paralanov Elizabeth A. Strychalski David Ross |
author_sort |
Jayan Rammohan |
title |
Comparison of bias and resolvability in single-cell and single-transcript methods |
title_short |
Comparison of bias and resolvability in single-cell and single-transcript methods |
title_full |
Comparison of bias and resolvability in single-cell and single-transcript methods |
title_fullStr |
Comparison of bias and resolvability in single-cell and single-transcript methods |
title_full_unstemmed |
Comparison of bias and resolvability in single-cell and single-transcript methods |
title_sort |
comparison of bias and resolvability in single-cell and single-transcript methods |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/18b4195254e744b8911081408a581ce2 |
work_keys_str_mv |
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_version_ |
1718385375161876480 |