Single-crosslink microscopy in a biopolymer network dissects local elasticity from molecular fluctuations

The intrinsic inhomogeneity of polymer networks is masked by the usual ensemble-averaged measurements. Here the authors construct direct maps of crosslinks in an actin network by selective labeling the crosslinks with fluorescent markers and characterize the local elasticity and cross-correlation be...

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Autores principales: Lingxiang Jiang, Qingqiao Xie, Boyce Tsang, Steve Granick
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/18b6db71920a45baa619b2fedbacd0cc
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Sumario:The intrinsic inhomogeneity of polymer networks is masked by the usual ensemble-averaged measurements. Here the authors construct direct maps of crosslinks in an actin network by selective labeling the crosslinks with fluorescent markers and characterize the local elasticity and cross-correlation between crosslinks.