Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila

Heterochromatin protein 1a (HP1a) is thought to function downstream of transposon repression in the Drosophila female germline. Here the authors show that HP1a also functions upstream of piRNA processing by repressing splicing of piRNA precursors, predominantly at telomeric and centromeric regions.

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Autores principales:	Ryan Yee Wei Teo, Amit Anand, Vishweshwaren Sridhar, Katsutomo Okamura, Toshie Kai
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/18b6e29e690a4b95a059b73a2718afe4
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spelling	oai:doaj.org-article:18b6e29e690a4b95a059b73a2718afe42021-12-02T15:34:01ZHeterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila10.1038/s41467-018-03908-32041-1723https://doaj.org/article/18b6e29e690a4b95a059b73a2718afe42018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03908-3https://doaj.org/toc/2041-1723Heterochromatin protein 1a (HP1a) is thought to function downstream of transposon repression in the Drosophila female germline. Here the authors show that HP1a also functions upstream of piRNA processing by repressing splicing of piRNA precursors, predominantly at telomeric and centromeric regions.Ryan Yee Wei TeoAmit AnandVishweshwaren SridharKatsutomo OkamuraToshie KaiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ryan Yee Wei Teo Amit Anand Vishweshwaren Sridhar Katsutomo Okamura Toshie Kai Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila
description	Heterochromatin protein 1a (HP1a) is thought to function downstream of transposon repression in the Drosophila female germline. Here the authors show that HP1a also functions upstream of piRNA processing by repressing splicing of piRNA precursors, predominantly at telomeric and centromeric regions.
format	article
author	Ryan Yee Wei Teo Amit Anand Vishweshwaren Sridhar Katsutomo Okamura Toshie Kai
author_facet	Ryan Yee Wei Teo Amit Anand Vishweshwaren Sridhar Katsutomo Okamura Toshie Kai
author_sort	Ryan Yee Wei Teo
title	Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila
title_short	Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila
title_full	Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila
title_fullStr	Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila
title_full_unstemmed	Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila
title_sort	heterochromatin protein 1a functions for pirna biogenesis predominantly from pericentric and telomeric regions in drosophila
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/18b6e29e690a4b95a059b73a2718afe4
work_keys_str_mv	AT ryanyeeweiteo heterochromatinprotein1afunctionsforpirnabiogenesispredominantlyfrompericentricandtelomericregionsindrosophila AT amitanand heterochromatinprotein1afunctionsforpirnabiogenesispredominantlyfrompericentricandtelomericregionsindrosophila AT vishweshwarensridhar heterochromatinprotein1afunctionsforpirnabiogenesispredominantlyfrompericentricandtelomericregionsindrosophila AT katsutomookamura heterochromatinprotein1afunctionsforpirnabiogenesispredominantlyfrompericentricandtelomericregionsindrosophila AT toshiekai heterochromatinprotein1afunctionsforpirnabiogenesispredominantlyfrompericentricandtelomericregionsindrosophila
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Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila

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