Beneficial effects of PCSK9 inhibition with alirocumab in familial hypercholesterolemia involve modulation of new immune players
Familial hypercholesterolemia (FH) is associated with low-grade systemic inflammation, a key driver of premature atherosclerosis. We investigated the effects of inhibiting proprotein convertase subtilisin/kexin type 9 (PCSK9) function on inflammatory state, endothelial dysfunction and cardiovascular...
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Autores principales: | , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Elsevier
2022
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Materias: | |
Acceso en línea: | https://doaj.org/article/18b9bb9d7ffb44ad935d98f1e616d8cd |
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