Sites of high local frustration in DNA origami

Self-assembly of DNA origami is a complex folding problem without a unified view of the energetic factors involved. Here the authors analyse identical structures that differ by nucleotide sequence and identify how mechanical stress at nucleation sites shapes the energy landscape.

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Autores principales: Richard Kosinski, Ann Mukhortava, Wolfgang Pfeifer, Andrea Candelli, Philipp Rauch, Barbara Saccà
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/18c3fb80b55445e2b7a1c1e064f84fa5
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