Actin dynamics provides membrane tension to merge fusing vesicles into the plasma membrane
As vesicles fuse to the plasma membrane, they form intermediate Ω-shaped structures followed by either closure of the pore or full merging with the plasma membrane. Here Wen et al. show that dynamic actin assembly provides membrane tension to promote Ω merging in neuroendocrine cells and synapses.
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Nature Portfolio
2016
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oai:doaj.org-article:18c51fe654d244e0aaf317965c19c8d02021-12-02T17:32:52ZActin dynamics provides membrane tension to merge fusing vesicles into the plasma membrane10.1038/ncomms126042041-1723https://doaj.org/article/18c51fe654d244e0aaf317965c19c8d02016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12604https://doaj.org/toc/2041-1723As vesicles fuse to the plasma membrane, they form intermediate Ω-shaped structures followed by either closure of the pore or full merging with the plasma membrane. Here Wen et al. show that dynamic actin assembly provides membrane tension to promote Ω merging in neuroendocrine cells and synapses.Peter J. WenStaffan GrenkloGianvito ArpinoXinyu TanHsien-Shun LiaoJohanna HeureauxShi-Yong PengHsueh-Cheng ChiangEdaeni HamidWei-Dong ZhaoWonchul ShinTuomas NäreojaEmma EvergrenYinghui JinRoger KarlssonSteven N. EbertAlbert JinAllen P. LiuOleg ShupliakovLing-Gang WuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Peter J. Wen Staffan Grenklo Gianvito Arpino Xinyu Tan Hsien-Shun Liao Johanna Heureaux Shi-Yong Peng Hsueh-Cheng Chiang Edaeni Hamid Wei-Dong Zhao Wonchul Shin Tuomas Näreoja Emma Evergren Yinghui Jin Roger Karlsson Steven N. Ebert Albert Jin Allen P. Liu Oleg Shupliakov Ling-Gang Wu Actin dynamics provides membrane tension to merge fusing vesicles into the plasma membrane |
| description |
As vesicles fuse to the plasma membrane, they form intermediate Ω-shaped structures followed by either closure of the pore or full merging with the plasma membrane. Here Wen et al. show that dynamic actin assembly provides membrane tension to promote Ω merging in neuroendocrine cells and synapses. |
| format |
article |
| author |
Peter J. Wen Staffan Grenklo Gianvito Arpino Xinyu Tan Hsien-Shun Liao Johanna Heureaux Shi-Yong Peng Hsueh-Cheng Chiang Edaeni Hamid Wei-Dong Zhao Wonchul Shin Tuomas Näreoja Emma Evergren Yinghui Jin Roger Karlsson Steven N. Ebert Albert Jin Allen P. Liu Oleg Shupliakov Ling-Gang Wu |
| author_facet |
Peter J. Wen Staffan Grenklo Gianvito Arpino Xinyu Tan Hsien-Shun Liao Johanna Heureaux Shi-Yong Peng Hsueh-Cheng Chiang Edaeni Hamid Wei-Dong Zhao Wonchul Shin Tuomas Näreoja Emma Evergren Yinghui Jin Roger Karlsson Steven N. Ebert Albert Jin Allen P. Liu Oleg Shupliakov Ling-Gang Wu |
| author_sort |
Peter J. Wen |
| title |
Actin dynamics provides membrane tension to merge fusing vesicles into the plasma membrane |
| title_short |
Actin dynamics provides membrane tension to merge fusing vesicles into the plasma membrane |
| title_full |
Actin dynamics provides membrane tension to merge fusing vesicles into the plasma membrane |
| title_fullStr |
Actin dynamics provides membrane tension to merge fusing vesicles into the plasma membrane |
| title_full_unstemmed |
Actin dynamics provides membrane tension to merge fusing vesicles into the plasma membrane |
| title_sort |
actin dynamics provides membrane tension to merge fusing vesicles into the plasma membrane |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/18c51fe654d244e0aaf317965c19c8d0 |
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