Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

Na+/H+antiporters transport sodium or lithium ions across the membrane in exchange for protons. Here the authors combine ion mobility mass spectrometry and molecular dynamics simulations to uncover a facilitating role for lipids in the transport mechanism.

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Detalles Bibliográficos
Autores principales: Michael Landreh, Erik G. Marklund, Povilas Uzdavinys, Matteo T. Degiacomi, Mathieu Coincon, Joseph Gault, Kallol Gupta, Idlir Liko, Justin L. P. Benesch, David Drew, Carol V. Robinson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/18c9b4bc2d6a40a58f92ba99e8020ab8
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https://doaj.org/article/18c9b4bc2d6a40a58f92ba99e8020ab8

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