USE OF 20 MINUTE WHOLE BLOOD CLOTTING TIME IN PATIENTS OF SNAKEBITE; AN EXPERIENCE FROM KOHAT, KHYBER PAKHTUNKHAH
Objective: To study the diagnostic accuracy of 20-minute whole blood clotting time in hemotoxic snakebite. Study Design: Cross sectional validation study. Place and Duration of Study: Combined Military Hospital Kohat Pakistan, from Jul 2015 to Jun 2017. Methodology: Study included 52 patien...
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| Autores principales: | , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Army Medical College Rawalpindi
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/18cdb6460f904fbdb4036400be650ff8 |
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| Sumario: | Objective: To study the diagnostic accuracy of 20-minute whole blood clotting time in hemotoxic snakebite.
Study Design: Cross sectional validation study.
Place and Duration of Study: Combined Military Hospital Kohat Pakistan, from Jul 2015 to Jun 2017.
Methodology: Study included 52 patients who presented with the complaint of a snakebite. The data was recorded on predesigned proforma including clinical, laboratory features. All the patients were kept indoor for observation for a minimum of 72 hours from the time of presentation.
Results: The study showed that males were more affected with age group between 20-50 years. Most common presenting features were local swelling 33 (71%) and pain and most common snakebite type was hemotoxic 33 (71%). The 20-minute whole blood clotting time was found to have low sensitivity (61%) and specificity (58%). A significant association was found between the dose of anti-snake venom and severity of coagulopathy (p<0.001), respiratory failure (p<0.001) and development of side effects due to anti snake venom (p<0.001). The mortality rate was 6.5% and was significantly related to age of the victims (p=0.003). The diagnostic accuracy of 20-minute whole blood clotting time was 60.25%.
Conclusion: The use of 20-minute whole blood clotting time can not only be misleading but also a source of delay in administering anti snake venom given the low sensitivity and specificity and high false negative rate. |
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