Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast

The core of the telomerase holoenzyme is composed of the reverse transcriptase and the non-coding RNA template. Here the authors identify Pof8 as a new constitutive component of fission yeast telomerase, loss of which causes telomerase assembly defects and critically short telomeres.

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Autores principales: Diego J. Páez-Moscoso, Lili Pan, Rutendo F. Sigauke, Morgan R. Schroeder, Wen Tang, Peter Baumann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/18ce1516edd445f982c03d13dbaa44f9
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spelling oai:doaj.org-article:18ce1516edd445f982c03d13dbaa44f92021-12-02T15:33:39ZPof8 is a La-related protein and a constitutive component of telomerase in fission yeast10.1038/s41467-017-02284-82041-1723https://doaj.org/article/18ce1516edd445f982c03d13dbaa44f92018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02284-8https://doaj.org/toc/2041-1723The core of the telomerase holoenzyme is composed of the reverse transcriptase and the non-coding RNA template. Here the authors identify Pof8 as a new constitutive component of fission yeast telomerase, loss of which causes telomerase assembly defects and critically short telomeres.Diego J. Páez-MoscosoLili PanRutendo F. SigaukeMorgan R. SchroederWen TangPeter BaumannNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Diego J. Páez-Moscoso
Lili Pan
Rutendo F. Sigauke
Morgan R. Schroeder
Wen Tang
Peter Baumann
Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast
description The core of the telomerase holoenzyme is composed of the reverse transcriptase and the non-coding RNA template. Here the authors identify Pof8 as a new constitutive component of fission yeast telomerase, loss of which causes telomerase assembly defects and critically short telomeres.
format article
author Diego J. Páez-Moscoso
Lili Pan
Rutendo F. Sigauke
Morgan R. Schroeder
Wen Tang
Peter Baumann
author_facet Diego J. Páez-Moscoso
Lili Pan
Rutendo F. Sigauke
Morgan R. Schroeder
Wen Tang
Peter Baumann
author_sort Diego J. Páez-Moscoso
title Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast
title_short Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast
title_full Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast
title_fullStr Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast
title_full_unstemmed Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast
title_sort pof8 is a la-related protein and a constitutive component of telomerase in fission yeast
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/18ce1516edd445f982c03d13dbaa44f9
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AT morganrschroeder pof8isalarelatedproteinandaconstitutivecomponentoftelomeraseinfissionyeast
AT wentang pof8isalarelatedproteinandaconstitutivecomponentoftelomeraseinfissionyeast
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