Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast
The core of the telomerase holoenzyme is composed of the reverse transcriptase and the non-coding RNA template. Here the authors identify Pof8 as a new constitutive component of fission yeast telomerase, loss of which causes telomerase assembly defects and critically short telomeres.
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Nature Portfolio
2018
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oai:doaj.org-article:18ce1516edd445f982c03d13dbaa44f92021-12-02T15:33:39ZPof8 is a La-related protein and a constitutive component of telomerase in fission yeast10.1038/s41467-017-02284-82041-1723https://doaj.org/article/18ce1516edd445f982c03d13dbaa44f92018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02284-8https://doaj.org/toc/2041-1723The core of the telomerase holoenzyme is composed of the reverse transcriptase and the non-coding RNA template. Here the authors identify Pof8 as a new constitutive component of fission yeast telomerase, loss of which causes telomerase assembly defects and critically short telomeres.Diego J. Páez-MoscosoLili PanRutendo F. SigaukeMorgan R. SchroederWen TangPeter BaumannNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Diego J. Páez-Moscoso Lili Pan Rutendo F. Sigauke Morgan R. Schroeder Wen Tang Peter Baumann Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast |
description |
The core of the telomerase holoenzyme is composed of the reverse transcriptase and the non-coding RNA template. Here the authors identify Pof8 as a new constitutive component of fission yeast telomerase, loss of which causes telomerase assembly defects and critically short telomeres. |
format |
article |
author |
Diego J. Páez-Moscoso Lili Pan Rutendo F. Sigauke Morgan R. Schroeder Wen Tang Peter Baumann |
author_facet |
Diego J. Páez-Moscoso Lili Pan Rutendo F. Sigauke Morgan R. Schroeder Wen Tang Peter Baumann |
author_sort |
Diego J. Páez-Moscoso |
title |
Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast |
title_short |
Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast |
title_full |
Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast |
title_fullStr |
Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast |
title_full_unstemmed |
Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast |
title_sort |
pof8 is a la-related protein and a constitutive component of telomerase in fission yeast |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/18ce1516edd445f982c03d13dbaa44f9 |
work_keys_str_mv |
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_version_ |
1718387008237207552 |