miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1

Kato, Abdollahi et al. identify a redox protein thioredoxin and mitochondrial fission-1 (FIS1) protein as miR-379 targets in mouse kidney. They find that miR-379 knockout mice are protected from diabetic kidney disease by enhancing mitophagy via FIS1, suggesting miR-379 as a potential therapeutic ta...

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Autores principales:	Mitsuo Kato, Maryam Abdollahi, Ragadeepthi Tunduguru, Walter Tsark, Zhuo Chen, Xiwei Wu, Jinhui Wang, Zhen Bouman Chen, Feng-Mao Lin, Linda Lanting, Mei Wang, Janice Huss, Patrick T Fueger, David Chan, Rama Natarajan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/18cedf624dff4f77b17af0446ccad171
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spelling	oai:doaj.org-article:18cedf624dff4f77b17af0446ccad1712021-12-02T15:07:32ZmiR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS110.1038/s42003-020-01516-w2399-3642https://doaj.org/article/18cedf624dff4f77b17af0446ccad1712021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01516-whttps://doaj.org/toc/2399-3642Kato, Abdollahi et al. identify a redox protein thioredoxin and mitochondrial fission-1 (FIS1) protein as miR-379 targets in mouse kidney. They find that miR-379 knockout mice are protected from diabetic kidney disease by enhancing mitophagy via FIS1, suggesting miR-379 as a potential therapeutic target for diabetic kidney disease.Mitsuo KatoMaryam AbdollahiRagadeepthi TunduguruWalter TsarkZhuo ChenXiwei WuJinhui WangZhen Bouman ChenFeng-Mao LinLinda LantingMei WangJanice HussPatrick T FuegerDavid ChanRama NatarajanNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Mitsuo Kato Maryam Abdollahi Ragadeepthi Tunduguru Walter Tsark Zhuo Chen Xiwei Wu Jinhui Wang Zhen Bouman Chen Feng-Mao Lin Linda Lanting Mei Wang Janice Huss Patrick T Fueger David Chan Rama Natarajan miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1
description	Kato, Abdollahi et al. identify a redox protein thioredoxin and mitochondrial fission-1 (FIS1) protein as miR-379 targets in mouse kidney. They find that miR-379 knockout mice are protected from diabetic kidney disease by enhancing mitophagy via FIS1, suggesting miR-379 as a potential therapeutic target for diabetic kidney disease.
format	article
author	Mitsuo Kato Maryam Abdollahi Ragadeepthi Tunduguru Walter Tsark Zhuo Chen Xiwei Wu Jinhui Wang Zhen Bouman Chen Feng-Mao Lin Linda Lanting Mei Wang Janice Huss Patrick T Fueger David Chan Rama Natarajan
author_facet	Mitsuo Kato Maryam Abdollahi Ragadeepthi Tunduguru Walter Tsark Zhuo Chen Xiwei Wu Jinhui Wang Zhen Bouman Chen Feng-Mao Lin Linda Lanting Mei Wang Janice Huss Patrick T Fueger David Chan Rama Natarajan
author_sort	Mitsuo Kato
title	miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1
title_short	miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1
title_full	miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1
title_fullStr	miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1
title_full_unstemmed	miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1
title_sort	mir-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via fis1
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/18cedf624dff4f77b17af0446ccad171
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miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1

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