Antimicrobial prophylaxis in addition to premedication in gastrointestinal surgery

The aim of this study was to evaluate three combinations of antibiotics applied perorally prior to laparotomy and gastrointestinal surgery and to select the most favorable combination. Research was performed on 24 female and male dogs divided into four groups. Following abdominal wall incision the c...

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Autores principales:	Genter Alan, Capak Hrvoje, Lipar Marija, Samardžija Marko, Harapin Ivica, Bedrica Ljiljana, Capak Darko
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2014
Materias:	antibiotics intestinal micro flora microbiology analysis Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/18cf358ed7964463960fd2b686426abb
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spelling	oai:doaj.org-article:18cf358ed7964463960fd2b686426abb2021-11-17T21:27:52ZAntimicrobial prophylaxis in addition to premedication in gastrointestinal surgery1820-744810.2478/acve-2014-0015https://doaj.org/article/18cf358ed7964463960fd2b686426abb2014-03-01T00:00:00Zhttps://doi.org/10.2478/acve-2014-0015https://doaj.org/toc/1820-7448The aim of this study was to evaluate three combinations of antibiotics applied perorally prior to laparotomy and gastrointestinal surgery and to select the most favorable combination. Research was performed on 24 female and male dogs divided into four groups. Following abdominal wall incision the caecum was compressed manually and 5 mL of saline solution was injected into it. Five mL of caecum contents was aspirated in a sterile syringe and only 0.1 mL was incubated into blood agar and homogenous agar. Bacterial colonies were counted and determined. Prior to surgery the control group (n=6) received no antibiotics. The group which received the combination of gentamicin and clindamycin (n=6) achieved the best reduction of E. coli whereas Enterococcus faecals was 100% destroyed. The group which received amoxicillin with clavulanic acid and metronidazole (n=6) acquired a reduction of bacteria Enterococcus faecalis, which could be sufficient for prophylaxis. The combination of gentamicin and erythromycin (n=6) failed to accomplish a reduction of the number of bacteria.Genter AlanCapak HrvojeLipar MarijaSamardžija MarkoHarapin IvicaBedrica LjiljanaCapak DarkoSciendoarticleantibioticsintestinal micro floramicrobiology analysisVeterinary medicineSF600-1100ENActa Veterinaria, Vol 64, Iss 1, Pp 149-155 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	antibiotics intestinal micro flora microbiology analysis Veterinary medicine SF600-1100
spellingShingle	antibiotics intestinal micro flora microbiology analysis Veterinary medicine SF600-1100 Genter Alan Capak Hrvoje Lipar Marija Samardžija Marko Harapin Ivica Bedrica Ljiljana Capak Darko Antimicrobial prophylaxis in addition to premedication in gastrointestinal surgery
description	The aim of this study was to evaluate three combinations of antibiotics applied perorally prior to laparotomy and gastrointestinal surgery and to select the most favorable combination. Research was performed on 24 female and male dogs divided into four groups. Following abdominal wall incision the caecum was compressed manually and 5 mL of saline solution was injected into it. Five mL of caecum contents was aspirated in a sterile syringe and only 0.1 mL was incubated into blood agar and homogenous agar. Bacterial colonies were counted and determined. Prior to surgery the control group (n=6) received no antibiotics. The group which received the combination of gentamicin and clindamycin (n=6) achieved the best reduction of E. coli whereas Enterococcus faecals was 100% destroyed. The group which received amoxicillin with clavulanic acid and metronidazole (n=6) acquired a reduction of bacteria Enterococcus faecalis, which could be sufficient for prophylaxis. The combination of gentamicin and erythromycin (n=6) failed to accomplish a reduction of the number of bacteria.
format	article
author	Genter Alan Capak Hrvoje Lipar Marija Samardžija Marko Harapin Ivica Bedrica Ljiljana Capak Darko
author_facet	Genter Alan Capak Hrvoje Lipar Marija Samardžija Marko Harapin Ivica Bedrica Ljiljana Capak Darko
author_sort	Genter Alan
title	Antimicrobial prophylaxis in addition to premedication in gastrointestinal surgery
title_short	Antimicrobial prophylaxis in addition to premedication in gastrointestinal surgery
title_full	Antimicrobial prophylaxis in addition to premedication in gastrointestinal surgery
title_fullStr	Antimicrobial prophylaxis in addition to premedication in gastrointestinal surgery
title_full_unstemmed	Antimicrobial prophylaxis in addition to premedication in gastrointestinal surgery
title_sort	antimicrobial prophylaxis in addition to premedication in gastrointestinal surgery
publisher	Sciendo
publishDate	2014
url	https://doaj.org/article/18cf358ed7964463960fd2b686426abb
work_keys_str_mv	AT genteralan antimicrobialprophylaxisinadditiontopremedicationingastrointestinalsurgery AT capakhrvoje antimicrobialprophylaxisinadditiontopremedicationingastrointestinalsurgery AT liparmarija antimicrobialprophylaxisinadditiontopremedicationingastrointestinalsurgery AT samardzijamarko antimicrobialprophylaxisinadditiontopremedicationingastrointestinalsurgery AT harapinivica antimicrobialprophylaxisinadditiontopremedicationingastrointestinalsurgery AT bedricaljiljana antimicrobialprophylaxisinadditiontopremedicationingastrointestinalsurgery AT capakdarko antimicrobialprophylaxisinadditiontopremedicationingastrointestinalsurgery
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Antimicrobial prophylaxis in addition to premedication in gastrointestinal surgery

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