The Salmonella type III effector SspH2 specifically exploits the NLR co-chaperone activity of SGT1 to subvert immunity.

To further its pathogenesis, S. Typhimurium delivers effector proteins into host cells, including the novel E3 ubiquitin ligase (NEL) effector SspH2. Using model systems in a cross-kingdom approach we gained further insight into the molecular function of this effector. Here, we show that SspH2 modul...

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Autores principales: Amit P Bhavsar, Nat F Brown, Jan Stoepel, Marcel Wiermer, Dale D O Martin, Karolynn J Hsu, Koshi Imami, Colin J Ross, Michael R Hayden, Leonard J Foster, Xin Li, Phil Hieter, B Brett Finlay
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/18d8300ef9bc4b3f815eb0cf4287600f
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