PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer

PTEN is often lost in prostate cancer. In this study, the authors show that PTEN can act as a protein phosphatase that targets active PTK6, thereby regulating its oncogenic signaling in prostate cancer progression.

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Detalles Bibliográficos
Autores principales:	Darren J. Wozniak, Andre Kajdacsy-Balla, Virgilia Macias, Susan Ball-Kell, Morgan L. Zenner, Wenjun Bie, Angela L. Tyner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/18dc9ef9edce4840868fb91007225a76
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spelling	oai:doaj.org-article:18dc9ef9edce4840868fb91007225a762021-12-02T15:38:57ZPTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer10.1038/s41467-017-01574-52041-1723https://doaj.org/article/18dc9ef9edce4840868fb91007225a762017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01574-5https://doaj.org/toc/2041-1723PTEN is often lost in prostate cancer. In this study, the authors show that PTEN can act as a protein phosphatase that targets active PTK6, thereby regulating its oncogenic signaling in prostate cancer progression.Darren J. WozniakAndre Kajdacsy-BallaVirgilia MaciasSusan Ball-KellMorgan L. ZennerWenjun BieAngela L. TynerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Darren J. Wozniak Andre Kajdacsy-Balla Virgilia Macias Susan Ball-Kell Morgan L. Zenner Wenjun Bie Angela L. Tyner PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer
description	PTEN is often lost in prostate cancer. In this study, the authors show that PTEN can act as a protein phosphatase that targets active PTK6, thereby regulating its oncogenic signaling in prostate cancer progression.
format	article
author	Darren J. Wozniak Andre Kajdacsy-Balla Virgilia Macias Susan Ball-Kell Morgan L. Zenner Wenjun Bie Angela L. Tyner
author_facet	Darren J. Wozniak Andre Kajdacsy-Balla Virgilia Macias Susan Ball-Kell Morgan L. Zenner Wenjun Bie Angela L. Tyner
author_sort	Darren J. Wozniak
title	PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer
title_short	PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer
title_full	PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer
title_fullStr	PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer
title_full_unstemmed	PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer
title_sort	pten is a protein phosphatase that targets active ptk6 and inhibits ptk6 oncogenic signaling in prostate cancer
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/18dc9ef9edce4840868fb91007225a76
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PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer

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