RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA

Abstract. We propose a protocol of treatment in cases of bronchial asthma with cytomegalovirus (CMV) persistence. This basic therapy is administered depending on the disease severity, according to the National Programme 2009. The treatment includes administration of human immunoglobulin, with dosage...

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Autores principales:	E. N. Suprun, V. K. Kozlov
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	bronchial asthma cytomegalovirus immunity children Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/18dd9d779875460cbcfde2357cf63e55
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spelling	oai:doaj.org-article:18dd9d779875460cbcfde2357cf63e552021-11-18T08:03:43ZRATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA1563-06252313-741X10.15789/1563-0625-2013-3-269-276https://doaj.org/article/18dd9d779875460cbcfde2357cf63e552014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/617https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. We propose a protocol of treatment in cases of bronchial asthma with cytomegalovirus (CMV) persistence. This basic therapy is administered depending on the disease severity, according to the National Programme 2009. The treatment includes administration of human immunoglobulin, with dosage according on CMV antibodies titers. The study has revealed that such regimen of antibody administration based on the content of anti-CMV antibodies in bronchial asthma treatment stops active CMV replication in bronchial mucous membrane, alleviates clinical course of the disease, diminishes changes of immune system typical to children suffering from bronchial asthma and CMV reactivation, thus allowing to reduce the volume of basic therapy, along with maintaining control of asthma control.E. N. SuprunV. K. KozlovSPb RAACIarticlebronchial asthmacytomegalovirusimmunitychildrenImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 15, Iss 3, Pp 269-276 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	bronchial asthma cytomegalovirus immunity children Immunologic diseases. Allergy RC581-607
spellingShingle	bronchial asthma cytomegalovirus immunity children Immunologic diseases. Allergy RC581-607 E. N. Suprun V. K. Kozlov RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA
description	Abstract. We propose a protocol of treatment in cases of bronchial asthma with cytomegalovirus (CMV) persistence. This basic therapy is administered depending on the disease severity, according to the National Programme 2009. The treatment includes administration of human immunoglobulin, with dosage according on CMV antibodies titers. The study has revealed that such regimen of antibody administration based on the content of anti-CMV antibodies in bronchial asthma treatment stops active CMV replication in bronchial mucous membrane, alleviates clinical course of the disease, diminishes changes of immune system typical to children suffering from bronchial asthma and CMV reactivation, thus allowing to reduce the volume of basic therapy, along with maintaining control of asthma control.
format	article
author	E. N. Suprun V. K. Kozlov
author_facet	E. N. Suprun V. K. Kozlov
author_sort	E. N. Suprun
title	RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA
title_short	RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA
title_full	RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA
title_fullStr	RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA
title_full_unstemmed	RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA
title_sort	rationale for a specific therapy of cytomegalovirus infection in children with bronchial asthma
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/18dd9d779875460cbcfde2357cf63e55
work_keys_str_mv	AT ensuprun rationaleforaspecifictherapyofcytomegalovirusinfectioninchildrenwithbronchialasthma AT vkkozlov rationaleforaspecifictherapyofcytomegalovirusinfectioninchildrenwithbronchialasthma
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RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA

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