Contribution of Nanotechnologies to Vaccine Development and Drug Delivery against Respiratory Viruses

According to the Center for Disease Control and Prevention (CDC), the coronavirus disease 2019, a respiratory viral illness linked to significant morbidity, mortality, production loss, and severe economic depression, was the third-largest cause of death in 2020. Respiratory viruses such as influenza...

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Autores principales: Mahdi Ftouh, Nesrine Kalboussi, Nabil Abid, Souad Sfar, Nathalie Mignet, Badr Bahloul
Formato: article
Lenguaje:EN
Publicado: Hindawi Limited 2021
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Acceso en línea:https://doaj.org/article/18de53fd7fc94969a3149e1c5c1668a2
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spelling oai:doaj.org-article:18de53fd7fc94969a3149e1c5c1668a22021-11-08T02:37:06ZContribution of Nanotechnologies to Vaccine Development and Drug Delivery against Respiratory Viruses1687-476510.1155/2021/6741290https://doaj.org/article/18de53fd7fc94969a3149e1c5c1668a22021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/6741290https://doaj.org/toc/1687-4765According to the Center for Disease Control and Prevention (CDC), the coronavirus disease 2019, a respiratory viral illness linked to significant morbidity, mortality, production loss, and severe economic depression, was the third-largest cause of death in 2020. Respiratory viruses such as influenza, respiratory syncytial virus, SARS-CoV-2, and adenovirus, are among the most common causes of respiratory illness in humans, spreading as pandemics or epidemics throughout all continents. Nanotechnologies are particles in the nanometer range made from various compositions. They can be lipid-based, polymer-based, protein-based, or inorganic in nature, but they are all bioinspired and virus-like. In this review, we aimed to present a short review of the different nanoparticles currently studied, in particular those which led to publications in the field of respiratory viruses. We evaluated those which could be beneficial for respiratory disease-based viruses; those which already have contributed, such as lipid nanoparticles in the context of COVID-19; and those which will contribute in the future either as vaccines or antiviral drug delivery systems. We present a short assessment based on a critical selection of evidence indicating nanotechnology’s promise in the prevention and treatment of respiratory infections.Mahdi FtouhNesrine KalboussiNabil AbidSouad SfarNathalie MignetBadr BahloulHindawi LimitedarticleBiology (General)QH301-705.5ENPPAR Research, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Mahdi Ftouh
Nesrine Kalboussi
Nabil Abid
Souad Sfar
Nathalie Mignet
Badr Bahloul
Contribution of Nanotechnologies to Vaccine Development and Drug Delivery against Respiratory Viruses
description According to the Center for Disease Control and Prevention (CDC), the coronavirus disease 2019, a respiratory viral illness linked to significant morbidity, mortality, production loss, and severe economic depression, was the third-largest cause of death in 2020. Respiratory viruses such as influenza, respiratory syncytial virus, SARS-CoV-2, and adenovirus, are among the most common causes of respiratory illness in humans, spreading as pandemics or epidemics throughout all continents. Nanotechnologies are particles in the nanometer range made from various compositions. They can be lipid-based, polymer-based, protein-based, or inorganic in nature, but they are all bioinspired and virus-like. In this review, we aimed to present a short review of the different nanoparticles currently studied, in particular those which led to publications in the field of respiratory viruses. We evaluated those which could be beneficial for respiratory disease-based viruses; those which already have contributed, such as lipid nanoparticles in the context of COVID-19; and those which will contribute in the future either as vaccines or antiviral drug delivery systems. We present a short assessment based on a critical selection of evidence indicating nanotechnology’s promise in the prevention and treatment of respiratory infections.
format article
author Mahdi Ftouh
Nesrine Kalboussi
Nabil Abid
Souad Sfar
Nathalie Mignet
Badr Bahloul
author_facet Mahdi Ftouh
Nesrine Kalboussi
Nabil Abid
Souad Sfar
Nathalie Mignet
Badr Bahloul
author_sort Mahdi Ftouh
title Contribution of Nanotechnologies to Vaccine Development and Drug Delivery against Respiratory Viruses
title_short Contribution of Nanotechnologies to Vaccine Development and Drug Delivery against Respiratory Viruses
title_full Contribution of Nanotechnologies to Vaccine Development and Drug Delivery against Respiratory Viruses
title_fullStr Contribution of Nanotechnologies to Vaccine Development and Drug Delivery against Respiratory Viruses
title_full_unstemmed Contribution of Nanotechnologies to Vaccine Development and Drug Delivery against Respiratory Viruses
title_sort contribution of nanotechnologies to vaccine development and drug delivery against respiratory viruses
publisher Hindawi Limited
publishDate 2021
url https://doaj.org/article/18de53fd7fc94969a3149e1c5c1668a2
work_keys_str_mv AT mahdiftouh contributionofnanotechnologiestovaccinedevelopmentanddrugdeliveryagainstrespiratoryviruses
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