Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples.

The quality of tissue samples and extracted mRNA is a major source of variability in tumor transcriptome analysis using genome-wide expression microarrays. During and immediately after surgical tumor resection, tissues are exposed to metabolic, biochemical and physical stresses characterized as &quo...

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Autores principales: Elodie Caboux, Maria Paciencia, Geoffroy Durand, Nivonirina Robinot, Magdalena B Wozniak, Françoise Galateau-Salle, Graham Byrnes, Pierre Hainaut, Florence Le Calvez-Kelm
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/18e496b5f0484fe89c3f3e7a112acbed
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