Apico-basal cell compression regulates Lamin A/C levels in epithelial tissues

The nuclear lamina bridges mechanical forces from the cytoskeleton to the nucleus, and while Lamin A/C is known to be crucial for this process, its regulation remains unclear. Here the authors show that levels of Lamin A/C scale with apico-basal compression of cells independently of tissue stiffness...

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Autores principales: K. Venkatesan Iyer, Anna Taubenberger, Salma Ahmed Zeidan, Natalie A. Dye, Suzanne Eaton, Frank Jülicher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/18f3dcd5533444a8967fe0f8c7d3ec46
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