Apico-basal cell compression regulates Lamin A/C levels in epithelial tissues

The nuclear lamina bridges mechanical forces from the cytoskeleton to the nucleus, and while Lamin A/C is known to be crucial for this process, its regulation remains unclear. Here the authors show that levels of Lamin A/C scale with apico-basal compression of cells independently of tissue stiffness...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: K. Venkatesan Iyer, Anna Taubenberger, Salma Ahmed Zeidan, Natalie A. Dye, Suzanne Eaton, Frank Jülicher
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Q
Accès en ligne:https://doaj.org/article/18f3dcd5533444a8967fe0f8c7d3ec46
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!