COVID-19-associated psychosis in Indian settings: A retrospective descriptive study

Background: The coronavirus-19 (COVID-19) pandemic has affected millions of people across the world since early 2020. Besides the large number of case fatalities, this virus has produced significant health-related sequelae involving multiple systems of the body. As with previous coronavirus infectio...

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Autores principales:	B K Dutta, R N Mani, S Sharma, V V Singh, T Aggarwal, H Chandra, Sweta Ratna, Sumit Sharma, A K Gupta
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	covid inflammation neuropsychiatric psychosis sequelae Psychiatry RC435-571 Industrial psychology HF5548.7-5548.85
Acceso en línea:	https://doaj.org/article/18f5a0e424734204883fe3ffbd5e12e7
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spelling	oai:doaj.org-article:18f5a0e424734204883fe3ffbd5e12e72021-11-12T10:11:30ZCOVID-19-associated psychosis in Indian settings: A retrospective descriptive study0972-67480976-279510.4103/0972-6748.328784https://doaj.org/article/18f5a0e424734204883fe3ffbd5e12e72021-01-01T00:00:00Zhttp://www.industrialpsychiatry.org/article.asp?issn=0972-6748;year=2021;volume=30;issue=3;spage=25;epage=28;aulast=Duttahttps://doaj.org/toc/0972-6748https://doaj.org/toc/0976-2795Background: The coronavirus-19 (COVID-19) pandemic has affected millions of people across the world since early 2020. Besides the large number of case fatalities, this virus has produced significant health-related sequelae involving multiple systems of the body. As with previous coronavirus infections, this was also found to be associated with various neuropsychiatric symptoms. Psychosis has been uncommon, and the few reported cases across the world have forwarded association with either raised inflammatory markers or the consequences of social isolation. Materials and Methods: This is a retrospective descriptive study of 12 patients, who were admitted with COVID-19 infection and psychosis, between March 2020 and December 2020. Cases of head injury, any neurological or metabolic illnesses, and substance use disorders were excluded. Results: Cases with psychosis formed only 0.19% of all cases of COVID-19 admissions. All of them were young male and employed. Most of them had abrupt onset of psychosis with confusion, delusions, hallucinations, agitation, and sleep disturbances. Investigations including inflammatory markers (C-reactive protein) and computerized tomography scans were largely normal. Medications used were mainly benzodiazepines and antipsychotics. Most of the cases resolved within the second week, and follow-up after a month did not elicit any residual symptoms in majority. Diagnosis was acute and transient psychotic disorder (about 75%), bipolar affective disorder (2 cases), and schizophrenia (one). Conclusions: The major findings included nonreactive inflammatory markers, quick resolution of symptoms, requirement of low doses of antipsychotic drugs, and no long-term sequelae.B K DuttaR N ManiS SharmaV V SinghT AggarwalH ChandraSweta RatnaSumit SharmaA K GuptaWolters Kluwer Medknow PublicationsarticlecovidinflammationneuropsychiatricpsychosissequelaePsychiatryRC435-571Industrial psychologyHF5548.7-5548.85ENIndustrial Psychiatry Journal, Vol 30, Iss 3, Pp 25-28 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	covid inflammation neuropsychiatric psychosis sequelae Psychiatry RC435-571 Industrial psychology HF5548.7-5548.85
spellingShingle	covid inflammation neuropsychiatric psychosis sequelae Psychiatry RC435-571 Industrial psychology HF5548.7-5548.85 B K Dutta R N Mani S Sharma V V Singh T Aggarwal H Chandra Sweta Ratna Sumit Sharma A K Gupta COVID-19-associated psychosis in Indian settings: A retrospective descriptive study
description	Background: The coronavirus-19 (COVID-19) pandemic has affected millions of people across the world since early 2020. Besides the large number of case fatalities, this virus has produced significant health-related sequelae involving multiple systems of the body. As with previous coronavirus infections, this was also found to be associated with various neuropsychiatric symptoms. Psychosis has been uncommon, and the few reported cases across the world have forwarded association with either raised inflammatory markers or the consequences of social isolation. Materials and Methods: This is a retrospective descriptive study of 12 patients, who were admitted with COVID-19 infection and psychosis, between March 2020 and December 2020. Cases of head injury, any neurological or metabolic illnesses, and substance use disorders were excluded. Results: Cases with psychosis formed only 0.19% of all cases of COVID-19 admissions. All of them were young male and employed. Most of them had abrupt onset of psychosis with confusion, delusions, hallucinations, agitation, and sleep disturbances. Investigations including inflammatory markers (C-reactive protein) and computerized tomography scans were largely normal. Medications used were mainly benzodiazepines and antipsychotics. Most of the cases resolved within the second week, and follow-up after a month did not elicit any residual symptoms in majority. Diagnosis was acute and transient psychotic disorder (about 75%), bipolar affective disorder (2 cases), and schizophrenia (one). Conclusions: The major findings included nonreactive inflammatory markers, quick resolution of symptoms, requirement of low doses of antipsychotic drugs, and no long-term sequelae.
format	article
author	B K Dutta R N Mani S Sharma V V Singh T Aggarwal H Chandra Sweta Ratna Sumit Sharma A K Gupta
author_facet	B K Dutta R N Mani S Sharma V V Singh T Aggarwal H Chandra Sweta Ratna Sumit Sharma A K Gupta
author_sort	B K Dutta
title	COVID-19-associated psychosis in Indian settings: A retrospective descriptive study
title_short	COVID-19-associated psychosis in Indian settings: A retrospective descriptive study
title_full	COVID-19-associated psychosis in Indian settings: A retrospective descriptive study
title_fullStr	COVID-19-associated psychosis in Indian settings: A retrospective descriptive study
title_full_unstemmed	COVID-19-associated psychosis in Indian settings: A retrospective descriptive study
title_sort	covid-19-associated psychosis in indian settings: a retrospective descriptive study
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/18f5a0e424734204883fe3ffbd5e12e7
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COVID-19-associated psychosis in Indian settings: A retrospective descriptive study

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