Simultaneous identification of multiple driver pathways in cancer.
Distinguishing the somatic mutations responsible for cancer (driver mutations) from random, passenger mutations is a key challenge in cancer genomics. Driver mutations generally target cellular signaling and regulatory pathways consisting of multiple genes. This heterogeneity complicates the identif...
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Autores principales: | Mark D M Leiserson, Dima Blokh, Roded Sharan, Benjamin J Raphael |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/18f6e798e1c848eeb0f54886920e4b89 |
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