Simultaneous identification of multiple driver pathways in cancer.

Distinguishing the somatic mutations responsible for cancer (driver mutations) from random, passenger mutations is a key challenge in cancer genomics. Driver mutations generally target cellular signaling and regulatory pathways consisting of multiple genes. This heterogeneity complicates the identif...

Full description

Saved in:
Bibliographic Details
Main Authors: Mark D M Leiserson, Dima Blokh, Roded Sharan, Benjamin J Raphael
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Online Access:https://doaj.org/article/18f6e798e1c848eeb0f54886920e4b89
Tags: Add Tag
No Tags, Be the first to tag this record!