The human nucleoporin Tpr protects cells from RNA-mediated replication stress
Tpr nucleoporin is known to be essential for nuclear transport and mitosis processes. Here the authors explore the link between Tpr and genome instability providing insights into the role of Tpr in safeguarding cells from RNA-mediated replication stress.
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Nature Portfolio
2021
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oai:doaj.org-article:18fbf66c3f8442a6835b1d14c7f9ffa22021-12-02T16:05:50ZThe human nucleoporin Tpr protects cells from RNA-mediated replication stress10.1038/s41467-021-24224-32041-1723https://doaj.org/article/18fbf66c3f8442a6835b1d14c7f9ffa22021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24224-3https://doaj.org/toc/2041-1723Tpr nucleoporin is known to be essential for nuclear transport and mitosis processes. Here the authors explore the link between Tpr and genome instability providing insights into the role of Tpr in safeguarding cells from RNA-mediated replication stress.Martin KosarMichele GiannattasioDaniele PicciniApolinar Maya-MendozaFrancisco García-BenítezJirina BartkovaSonia I. BarrosoHélène GaillardEmanuele MartiniUmberto RestucciaMiguel Angel Ramirez-OteroMassimiliano GarreEleonora VergaMiguel Andújar-SánchezScott MaynardZdenek HodnyVincenzo CostanzoAmit KumarAngela BachiAndrés AguileraJiri BartekMarco FoianiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
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Science Q Martin Kosar Michele Giannattasio Daniele Piccini Apolinar Maya-Mendoza Francisco García-Benítez Jirina Bartkova Sonia I. Barroso Hélène Gaillard Emanuele Martini Umberto Restuccia Miguel Angel Ramirez-Otero Massimiliano Garre Eleonora Verga Miguel Andújar-Sánchez Scott Maynard Zdenek Hodny Vincenzo Costanzo Amit Kumar Angela Bachi Andrés Aguilera Jiri Bartek Marco Foiani The human nucleoporin Tpr protects cells from RNA-mediated replication stress |
description |
Tpr nucleoporin is known to be essential for nuclear transport and mitosis processes. Here the authors explore the link between Tpr and genome instability providing insights into the role of Tpr in safeguarding cells from RNA-mediated replication stress. |
format |
article |
author |
Martin Kosar Michele Giannattasio Daniele Piccini Apolinar Maya-Mendoza Francisco García-Benítez Jirina Bartkova Sonia I. Barroso Hélène Gaillard Emanuele Martini Umberto Restuccia Miguel Angel Ramirez-Otero Massimiliano Garre Eleonora Verga Miguel Andújar-Sánchez Scott Maynard Zdenek Hodny Vincenzo Costanzo Amit Kumar Angela Bachi Andrés Aguilera Jiri Bartek Marco Foiani |
author_facet |
Martin Kosar Michele Giannattasio Daniele Piccini Apolinar Maya-Mendoza Francisco García-Benítez Jirina Bartkova Sonia I. Barroso Hélène Gaillard Emanuele Martini Umberto Restuccia Miguel Angel Ramirez-Otero Massimiliano Garre Eleonora Verga Miguel Andújar-Sánchez Scott Maynard Zdenek Hodny Vincenzo Costanzo Amit Kumar Angela Bachi Andrés Aguilera Jiri Bartek Marco Foiani |
author_sort |
Martin Kosar |
title |
The human nucleoporin Tpr protects cells from RNA-mediated replication stress |
title_short |
The human nucleoporin Tpr protects cells from RNA-mediated replication stress |
title_full |
The human nucleoporin Tpr protects cells from RNA-mediated replication stress |
title_fullStr |
The human nucleoporin Tpr protects cells from RNA-mediated replication stress |
title_full_unstemmed |
The human nucleoporin Tpr protects cells from RNA-mediated replication stress |
title_sort |
human nucleoporin tpr protects cells from rna-mediated replication stress |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/18fbf66c3f8442a6835b1d14c7f9ffa2 |
work_keys_str_mv |
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