High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue
While strain is known to affect cardiac electrophysiology, experimental systems to interrogate the effect of rapid strain cycles on cardiac tissue are lacking. Here the authors introduce a multielectrode array that can induce rapid dynamic strain cycles on cardiomyocyte strands and see effects of st...
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Nature Portfolio
2019
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oai:doaj.org-article:1901c6b298734f24aab8bad39352e00c2021-12-02T17:01:51ZHigh-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue10.1038/s41467-019-08757-22041-1723https://doaj.org/article/1901c6b298734f24aab8bad39352e00c2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08757-2https://doaj.org/toc/2041-1723While strain is known to affect cardiac electrophysiology, experimental systems to interrogate the effect of rapid strain cycles on cardiac tissue are lacking. Here the authors introduce a multielectrode array that can induce rapid dynamic strain cycles on cardiomyocyte strands and see effects of strain amplitude but not strain rate on impulse conduction.Matthias ImbodenEtienne de CoulonAlexandre PoulinChristian DellenbachSamuel RossetHerbert SheaStephan RohrNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
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Science Q Matthias Imboden Etienne de Coulon Alexandre Poulin Christian Dellenbach Samuel Rosset Herbert Shea Stephan Rohr High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue |
description |
While strain is known to affect cardiac electrophysiology, experimental systems to interrogate the effect of rapid strain cycles on cardiac tissue are lacking. Here the authors introduce a multielectrode array that can induce rapid dynamic strain cycles on cardiomyocyte strands and see effects of strain amplitude but not strain rate on impulse conduction. |
format |
article |
author |
Matthias Imboden Etienne de Coulon Alexandre Poulin Christian Dellenbach Samuel Rosset Herbert Shea Stephan Rohr |
author_facet |
Matthias Imboden Etienne de Coulon Alexandre Poulin Christian Dellenbach Samuel Rosset Herbert Shea Stephan Rohr |
author_sort |
Matthias Imboden |
title |
High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue |
title_short |
High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue |
title_full |
High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue |
title_fullStr |
High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue |
title_full_unstemmed |
High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue |
title_sort |
high-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/1901c6b298734f24aab8bad39352e00c |
work_keys_str_mv |
AT matthiasimboden highspeedmechanoactivemultielectrodearrayforinvestigatingrapidstretcheffectsoncardiactissue AT etiennedecoulon highspeedmechanoactivemultielectrodearrayforinvestigatingrapidstretcheffectsoncardiactissue AT alexandrepoulin highspeedmechanoactivemultielectrodearrayforinvestigatingrapidstretcheffectsoncardiactissue AT christiandellenbach highspeedmechanoactivemultielectrodearrayforinvestigatingrapidstretcheffectsoncardiactissue AT samuelrosset highspeedmechanoactivemultielectrodearrayforinvestigatingrapidstretcheffectsoncardiactissue AT herbertshea highspeedmechanoactivemultielectrodearrayforinvestigatingrapidstretcheffectsoncardiactissue AT stephanrohr highspeedmechanoactivemultielectrodearrayforinvestigatingrapidstretcheffectsoncardiactissue |
_version_ |
1718382012711043072 |