High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue

While strain is known to affect cardiac electrophysiology, experimental systems to interrogate the effect of rapid strain cycles on cardiac tissue are lacking. Here the authors introduce a multielectrode array that can induce rapid dynamic strain cycles on cardiomyocyte strands and see effects of st...

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Autores principales: Matthias Imboden, Etienne de Coulon, Alexandre Poulin, Christian Dellenbach, Samuel Rosset, Herbert Shea, Stephan Rohr
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1901c6b298734f24aab8bad39352e00c
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spelling oai:doaj.org-article:1901c6b298734f24aab8bad39352e00c2021-12-02T17:01:51ZHigh-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue10.1038/s41467-019-08757-22041-1723https://doaj.org/article/1901c6b298734f24aab8bad39352e00c2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08757-2https://doaj.org/toc/2041-1723While strain is known to affect cardiac electrophysiology, experimental systems to interrogate the effect of rapid strain cycles on cardiac tissue are lacking. Here the authors introduce a multielectrode array that can induce rapid dynamic strain cycles on cardiomyocyte strands and see effects of strain amplitude but not strain rate on impulse conduction.Matthias ImbodenEtienne de CoulonAlexandre PoulinChristian DellenbachSamuel RossetHerbert SheaStephan RohrNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Matthias Imboden
Etienne de Coulon
Alexandre Poulin
Christian Dellenbach
Samuel Rosset
Herbert Shea
Stephan Rohr
High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue
description While strain is known to affect cardiac electrophysiology, experimental systems to interrogate the effect of rapid strain cycles on cardiac tissue are lacking. Here the authors introduce a multielectrode array that can induce rapid dynamic strain cycles on cardiomyocyte strands and see effects of strain amplitude but not strain rate on impulse conduction.
format article
author Matthias Imboden
Etienne de Coulon
Alexandre Poulin
Christian Dellenbach
Samuel Rosset
Herbert Shea
Stephan Rohr
author_facet Matthias Imboden
Etienne de Coulon
Alexandre Poulin
Christian Dellenbach
Samuel Rosset
Herbert Shea
Stephan Rohr
author_sort Matthias Imboden
title High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue
title_short High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue
title_full High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue
title_fullStr High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue
title_full_unstemmed High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue
title_sort high-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/1901c6b298734f24aab8bad39352e00c
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