A role for amyloid in cell aggregation and biofilm formation.

A role for amyloid in cell aggregation and biofilm formation.

Cell adhesion molecules in Saccharomyces cerevisiae and Candida albicans contain amyloid-forming sequences that are highly conserved. We have now used site-specific mutagenesis and specific peptide perturbants to explore amyloid-dependent activity in the Candida albicans adhesin Als5p. A V326N subst...

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Autores principales: Melissa C Garcia, Janis T Lee, Caleen B Ramsook, David Alsteens, Yves F Dufrêne, Peter N Lipke
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/19133788e2fa4d24be8b67f7deab60de
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