Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers

The vesicles that transport proteins between intracellular organelles are small, short-lived, and elusive. Here, the authors show that capture of these vesicles through relocalizing tethers to mitochondria allows their contents to be characterised by organelle proteomics.

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Autores principales: John J. H. Shin, Oliver M. Crook, Alicia C. Borgeaud, Jérôme Cattin-Ortolá, Sew Y. Peak-Chew, Lisa M. Breckels, Alison K. Gillingham, Jessica Chadwick, Kathryn S. Lilley, Sean Munro
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/1913f75e498144daac7560db0fab4bbd
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spelling oai:doaj.org-article:1913f75e498144daac7560db0fab4bbd2021-12-02T10:48:11ZSpatial proteomics defines the content of trafficking vesicles captured by golgin tethers10.1038/s41467-020-19840-42041-1723https://doaj.org/article/1913f75e498144daac7560db0fab4bbd2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19840-4https://doaj.org/toc/2041-1723The vesicles that transport proteins between intracellular organelles are small, short-lived, and elusive. Here, the authors show that capture of these vesicles through relocalizing tethers to mitochondria allows their contents to be characterised by organelle proteomics.John J. H. ShinOliver M. CrookAlicia C. BorgeaudJérôme Cattin-OrtoláSew Y. Peak-ChewLisa M. BreckelsAlison K. GillinghamJessica ChadwickKathryn S. LilleySean MunroNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
John J. H. Shin
Oliver M. Crook
Alicia C. Borgeaud
Jérôme Cattin-Ortolá
Sew Y. Peak-Chew
Lisa M. Breckels
Alison K. Gillingham
Jessica Chadwick
Kathryn S. Lilley
Sean Munro
Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers
description The vesicles that transport proteins between intracellular organelles are small, short-lived, and elusive. Here, the authors show that capture of these vesicles through relocalizing tethers to mitochondria allows their contents to be characterised by organelle proteomics.
format article
author John J. H. Shin
Oliver M. Crook
Alicia C. Borgeaud
Jérôme Cattin-Ortolá
Sew Y. Peak-Chew
Lisa M. Breckels
Alison K. Gillingham
Jessica Chadwick
Kathryn S. Lilley
Sean Munro
author_facet John J. H. Shin
Oliver M. Crook
Alicia C. Borgeaud
Jérôme Cattin-Ortolá
Sew Y. Peak-Chew
Lisa M. Breckels
Alison K. Gillingham
Jessica Chadwick
Kathryn S. Lilley
Sean Munro
author_sort John J. H. Shin
title Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers
title_short Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers
title_full Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers
title_fullStr Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers
title_full_unstemmed Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers
title_sort spatial proteomics defines the content of trafficking vesicles captured by golgin tethers
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/1913f75e498144daac7560db0fab4bbd
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