Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers
The vesicles that transport proteins between intracellular organelles are small, short-lived, and elusive. Here, the authors show that capture of these vesicles through relocalizing tethers to mitochondria allows their contents to be characterised by organelle proteomics.
Guardado en:
Autores principales: | , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1913f75e498144daac7560db0fab4bbd |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:1913f75e498144daac7560db0fab4bbd |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:1913f75e498144daac7560db0fab4bbd2021-12-02T10:48:11ZSpatial proteomics defines the content of trafficking vesicles captured by golgin tethers10.1038/s41467-020-19840-42041-1723https://doaj.org/article/1913f75e498144daac7560db0fab4bbd2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19840-4https://doaj.org/toc/2041-1723The vesicles that transport proteins between intracellular organelles are small, short-lived, and elusive. Here, the authors show that capture of these vesicles through relocalizing tethers to mitochondria allows their contents to be characterised by organelle proteomics.John J. H. ShinOliver M. CrookAlicia C. BorgeaudJérôme Cattin-OrtoláSew Y. Peak-ChewLisa M. BreckelsAlison K. GillinghamJessica ChadwickKathryn S. LilleySean MunroNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q John J. H. Shin Oliver M. Crook Alicia C. Borgeaud Jérôme Cattin-Ortolá Sew Y. Peak-Chew Lisa M. Breckels Alison K. Gillingham Jessica Chadwick Kathryn S. Lilley Sean Munro Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers |
description |
The vesicles that transport proteins between intracellular organelles are small, short-lived, and elusive. Here, the authors show that capture of these vesicles through relocalizing tethers to mitochondria allows their contents to be characterised by organelle proteomics. |
format |
article |
author |
John J. H. Shin Oliver M. Crook Alicia C. Borgeaud Jérôme Cattin-Ortolá Sew Y. Peak-Chew Lisa M. Breckels Alison K. Gillingham Jessica Chadwick Kathryn S. Lilley Sean Munro |
author_facet |
John J. H. Shin Oliver M. Crook Alicia C. Borgeaud Jérôme Cattin-Ortolá Sew Y. Peak-Chew Lisa M. Breckels Alison K. Gillingham Jessica Chadwick Kathryn S. Lilley Sean Munro |
author_sort |
John J. H. Shin |
title |
Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers |
title_short |
Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers |
title_full |
Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers |
title_fullStr |
Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers |
title_full_unstemmed |
Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers |
title_sort |
spatial proteomics defines the content of trafficking vesicles captured by golgin tethers |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/1913f75e498144daac7560db0fab4bbd |
work_keys_str_mv |
AT johnjhshin spatialproteomicsdefinesthecontentoftraffickingvesiclescapturedbygolgintethers AT olivermcrook spatialproteomicsdefinesthecontentoftraffickingvesiclescapturedbygolgintethers AT aliciacborgeaud spatialproteomicsdefinesthecontentoftraffickingvesiclescapturedbygolgintethers AT jeromecattinortola spatialproteomicsdefinesthecontentoftraffickingvesiclescapturedbygolgintethers AT sewypeakchew spatialproteomicsdefinesthecontentoftraffickingvesiclescapturedbygolgintethers AT lisambreckels spatialproteomicsdefinesthecontentoftraffickingvesiclescapturedbygolgintethers AT alisonkgillingham spatialproteomicsdefinesthecontentoftraffickingvesiclescapturedbygolgintethers AT jessicachadwick spatialproteomicsdefinesthecontentoftraffickingvesiclescapturedbygolgintethers AT kathrynslilley spatialproteomicsdefinesthecontentoftraffickingvesiclescapturedbygolgintethers AT seanmunro spatialproteomicsdefinesthecontentoftraffickingvesiclescapturedbygolgintethers |
_version_ |
1718396633047105536 |