Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma

Tumour-infiltrating lymphocytes play a crucial role in neuroblastoma, but their relationship to other immune cells is poorly understood. Here the authors identify the cellular and gene signatures of intratumoural dendritic cells and natural killer cells that predict the clinical outcome of neuroblas...

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Autores principales: Ombretta Melaiu, Marco Chierici, Valeria Lucarini, Giuseppe Jurman, Libenzio Adrian Conti, Rita De Vito, Renata Boldrini, Loredana Cifaldi, Aurora Castellano, Cesare Furlanello, Vincenzo Barnaba, Franco Locatelli, Doriana Fruci
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/191708cfe4614fcda62e11c1850f8185
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spelling oai:doaj.org-article:191708cfe4614fcda62e11c1850f81852021-12-02T10:47:52ZCellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma10.1038/s41467-020-19781-y2041-1723https://doaj.org/article/191708cfe4614fcda62e11c1850f81852020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19781-yhttps://doaj.org/toc/2041-1723Tumour-infiltrating lymphocytes play a crucial role in neuroblastoma, but their relationship to other immune cells is poorly understood. Here the authors identify the cellular and gene signatures of intratumoural dendritic cells and natural killer cells that predict the clinical outcome of neuroblastoma.Ombretta MelaiuMarco ChiericiValeria LucariniGiuseppe JurmanLibenzio Adrian ContiRita De VitoRenata BoldriniLoredana CifaldiAurora CastellanoCesare FurlanelloVincenzo BarnabaFranco LocatelliDoriana FruciNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ombretta Melaiu
Marco Chierici
Valeria Lucarini
Giuseppe Jurman
Libenzio Adrian Conti
Rita De Vito
Renata Boldrini
Loredana Cifaldi
Aurora Castellano
Cesare Furlanello
Vincenzo Barnaba
Franco Locatelli
Doriana Fruci
Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma
description Tumour-infiltrating lymphocytes play a crucial role in neuroblastoma, but their relationship to other immune cells is poorly understood. Here the authors identify the cellular and gene signatures of intratumoural dendritic cells and natural killer cells that predict the clinical outcome of neuroblastoma.
format article
author Ombretta Melaiu
Marco Chierici
Valeria Lucarini
Giuseppe Jurman
Libenzio Adrian Conti
Rita De Vito
Renata Boldrini
Loredana Cifaldi
Aurora Castellano
Cesare Furlanello
Vincenzo Barnaba
Franco Locatelli
Doriana Fruci
author_facet Ombretta Melaiu
Marco Chierici
Valeria Lucarini
Giuseppe Jurman
Libenzio Adrian Conti
Rita De Vito
Renata Boldrini
Loredana Cifaldi
Aurora Castellano
Cesare Furlanello
Vincenzo Barnaba
Franco Locatelli
Doriana Fruci
author_sort Ombretta Melaiu
title Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma
title_short Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma
title_full Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma
title_fullStr Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma
title_full_unstemmed Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma
title_sort cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/191708cfe4614fcda62e11c1850f8185
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