Catalytic asymmetric nucleophilic fluorination using BF3·Et2O as fluorine source and activating reagent

Catalytic asymmetric nucleophilic fluorination using BF3·Et2O as fluorine source and activating reagent

Catalytic asymmetric fluorination remains elusive, especially the longstanding stereochemical challenges which exist in BF3Et2O-based fluorinations. Here the authors show a catalytic asymmetric nucleophilic fluorination using BF3·Et2O as the fluorine reagent in the presence of chiral iodine catalyst...

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Autores principales: Weiwei Zhu, Xiang Zhen, Jingyuan Wu, Yaping Cheng, Junkai An, Xingyu Ma, Jikun Liu, Yuji Qin, Hao Zhu, Jijun Xue, Xianxing Jiang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/192debc183404b709840ddf4ba15cc9e
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