Spatial expression analyses of the putative oncogene ciRS-7 in cancer reshape the microRNA sponge theory

The circular RNA named ciRS-7 is overexpressed in human cancers, however, its spatial cellular expression patterns have not been explored. Here, the authors show that ciRS-7 is not expressed in colon cancer cells, but abundant in stromal cells within tumours, and that cancer-to-stromal cell ratios c...

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Autores principales: Lasse S. Kristensen, Karoline K. Ebbesen, Martin Sokol, Theresa Jakobsen, Ulrik Korsgaard, Ann C. Eriksen, Thomas B. Hansen, Jørgen Kjems, Henrik Hager
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/1936aeae5ae645e7b1b908e2113e8300
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