SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses

Currently very little is known about how our immune system responds to SARS-CoV-2 infection. Here the authors generate a SARS-CoV-2 proteome microarray for profiling of IgG and IgM responses to COVID-19 in patients and find significant responses to ORF9b and NSP5, as well as the S1 and N proteins.

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Autores principales: He-wei Jiang, Yang Li, Hai-nan Zhang, Wei Wang, Xiao Yang, Huan Qi, Hua Li, Dong Men, Jie Zhou, Sheng-ce Tao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/193a0267d89b4f5c9342c3e83ef4d114
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Sumario:Currently very little is known about how our immune system responds to SARS-CoV-2 infection. Here the authors generate a SARS-CoV-2 proteome microarray for profiling of IgG and IgM responses to COVID-19 in patients and find significant responses to ORF9b and NSP5, as well as the S1 and N proteins.