SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses

Currently very little is known about how our immune system responds to SARS-CoV-2 infection. Here the authors generate a SARS-CoV-2 proteome microarray for profiling of IgG and IgM responses to COVID-19 in patients and find significant responses to ORF9b and NSP5, as well as the S1 and N proteins.

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Autores principales: He-wei Jiang, Yang Li, Hai-nan Zhang, Wei Wang, Xiao Yang, Huan Qi, Hua Li, Dong Men, Jie Zhou, Sheng-ce Tao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/193a0267d89b4f5c9342c3e83ef4d114
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spelling oai:doaj.org-article:193a0267d89b4f5c9342c3e83ef4d1142021-12-02T15:33:17ZSARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses10.1038/s41467-020-17488-82041-1723https://doaj.org/article/193a0267d89b4f5c9342c3e83ef4d1142020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17488-8https://doaj.org/toc/2041-1723Currently very little is known about how our immune system responds to SARS-CoV-2 infection. Here the authors generate a SARS-CoV-2 proteome microarray for profiling of IgG and IgM responses to COVID-19 in patients and find significant responses to ORF9b and NSP5, as well as the S1 and N proteins.He-wei JiangYang LiHai-nan ZhangWei WangXiao YangHuan QiHua LiDong MenJie ZhouSheng-ce TaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
He-wei Jiang
Yang Li
Hai-nan Zhang
Wei Wang
Xiao Yang
Huan Qi
Hua Li
Dong Men
Jie Zhou
Sheng-ce Tao
SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses
description Currently very little is known about how our immune system responds to SARS-CoV-2 infection. Here the authors generate a SARS-CoV-2 proteome microarray for profiling of IgG and IgM responses to COVID-19 in patients and find significant responses to ORF9b and NSP5, as well as the S1 and N proteins.
format article
author He-wei Jiang
Yang Li
Hai-nan Zhang
Wei Wang
Xiao Yang
Huan Qi
Hua Li
Dong Men
Jie Zhou
Sheng-ce Tao
author_facet He-wei Jiang
Yang Li
Hai-nan Zhang
Wei Wang
Xiao Yang
Huan Qi
Hua Li
Dong Men
Jie Zhou
Sheng-ce Tao
author_sort He-wei Jiang
title SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses
title_short SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses
title_full SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses
title_fullStr SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses
title_full_unstemmed SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses
title_sort sars-cov-2 proteome microarray for global profiling of covid-19 specific igg and igm responses
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/193a0267d89b4f5c9342c3e83ef4d114
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