Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage

Mutation of the nuclear envelope protein, barrier-to-autointegration factor 1 (Banf1), has previously been associated with the development of ageing associated diseases in a human progeria syndrome. Here, the authors reveal the functional link between Banf1-regulated, PARP1-directed repair of oxidat...

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Autores principales: Emma Bolderson, Joshua T. Burgess, Jun Li, Neha S. Gandhi, Didier Boucher, Laura V. Croft, Samuel Beard, Jennifer J. Plowman, Amila Suraweera, Mark N. Adams, Ali Naqi, Shu-Dong Zhang, David A. Sinclair, Kenneth J. O’Byrne, Derek J. Richard
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/193e27c4cfec497c9a58e98a20dcfe50
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spelling oai:doaj.org-article:193e27c4cfec497c9a58e98a20dcfe502021-12-02T14:39:40ZBarrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage10.1038/s41467-019-13167-52041-1723https://doaj.org/article/193e27c4cfec497c9a58e98a20dcfe502019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13167-5https://doaj.org/toc/2041-1723Mutation of the nuclear envelope protein, barrier-to-autointegration factor 1 (Banf1), has previously been associated with the development of ageing associated diseases in a human progeria syndrome. Here, the authors reveal the functional link between Banf1-regulated, PARP1-directed repair of oxidative lesions.Emma BoldersonJoshua T. BurgessJun LiNeha S. GandhiDidier BoucherLaura V. CroftSamuel BeardJennifer J. PlowmanAmila SuraweeraMark N. AdamsAli NaqiShu-Dong ZhangDavid A. SinclairKenneth J. O’ByrneDerek J. RichardNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Emma Bolderson
Joshua T. Burgess
Jun Li
Neha S. Gandhi
Didier Boucher
Laura V. Croft
Samuel Beard
Jennifer J. Plowman
Amila Suraweera
Mark N. Adams
Ali Naqi
Shu-Dong Zhang
David A. Sinclair
Kenneth J. O’Byrne
Derek J. Richard
Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
description Mutation of the nuclear envelope protein, barrier-to-autointegration factor 1 (Banf1), has previously been associated with the development of ageing associated diseases in a human progeria syndrome. Here, the authors reveal the functional link between Banf1-regulated, PARP1-directed repair of oxidative lesions.
format article
author Emma Bolderson
Joshua T. Burgess
Jun Li
Neha S. Gandhi
Didier Boucher
Laura V. Croft
Samuel Beard
Jennifer J. Plowman
Amila Suraweera
Mark N. Adams
Ali Naqi
Shu-Dong Zhang
David A. Sinclair
Kenneth J. O’Byrne
Derek J. Richard
author_facet Emma Bolderson
Joshua T. Burgess
Jun Li
Neha S. Gandhi
Didier Boucher
Laura V. Croft
Samuel Beard
Jennifer J. Plowman
Amila Suraweera
Mark N. Adams
Ali Naqi
Shu-Dong Zhang
David A. Sinclair
Kenneth J. O’Byrne
Derek J. Richard
author_sort Emma Bolderson
title Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
title_short Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
title_full Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
title_fullStr Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
title_full_unstemmed Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
title_sort barrier-to-autointegration factor 1 (banf1) regulates poly [adp-ribose] polymerase 1 (parp1) activity following oxidative dna damage
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/193e27c4cfec497c9a58e98a20dcfe50
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