Differences in in vitro microglial accumulation of the energy metabolism tracers [18F]FDG and [18F]BCPP-EF during LPS- and IL4 stimulation

Abstract The positron emission tomography probes 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) and 2-tert-butyl-4-chloro-5-{6-[2-(2-[18F]fluoroethoxy)-ethoxy]-pyridin-3-ylmethoxy}-2H-pyridazin-3-one ([18F]BCPP-EF) are designed to evaluate glycolysis and oxidative phosphorylation, respectively, and are...

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Autores principales: Chie Suzuki, Sarina Han, Gandhervin Kesavamoorthy, Mutsumi Kosugi, Kaori Araki, Norihiro Harada, Masakatsu Kanazawa, Hideo Tsukada, Yasuhiro Magata, Yasuomi Ouchi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/19461eedfa4b4b40ba27aa860c1c7720
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