Cellular macromolecules-tethered DNA walking indexing to explore nanoenvironments of chromatin modifications

Investigation of spatial organization and relationships of biomolecules in cellular nanoenvironments is necessary to understand essential biological processes, but methodologically challenging. Here, the authors report cellular macromolecules-tethered DNA walking indexing (Cell-TALKING) to probe the...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Feng Chen, Min Bai, Xiaowen Cao, Jing Xue, Yue Zhao, Na Wu, Lei Wang, Dexin Zhang, Yongxi Zhao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1952b4348f4f496eb3d2dfe01f4ec6b8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1952b4348f4f496eb3d2dfe01f4ec6b8
record_format	dspace
spelling	oai:doaj.org-article:1952b4348f4f496eb3d2dfe01f4ec6b82021-12-02T18:18:03ZCellular macromolecules-tethered DNA walking indexing to explore nanoenvironments of chromatin modifications10.1038/s41467-021-22284-z2041-1723https://doaj.org/article/1952b4348f4f496eb3d2dfe01f4ec6b82021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22284-zhttps://doaj.org/toc/2041-1723Investigation of spatial organization and relationships of biomolecules in cellular nanoenvironments is necessary to understand essential biological processes, but methodologically challenging. Here, the authors report cellular macromolecules-tethered DNA walking indexing (Cell-TALKING) to probe the nanoenvironments of DNA modifications around histone post-translational modifications, and explore the nanoenvironments in different cancer cell lines and clinical specimens.Feng ChenMin BaiXiaowen CaoJing XueYue ZhaoNa WuLei WangDexin ZhangYongxi ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Feng Chen Min Bai Xiaowen Cao Jing Xue Yue Zhao Na Wu Lei Wang Dexin Zhang Yongxi Zhao Cellular macromolecules-tethered DNA walking indexing to explore nanoenvironments of chromatin modifications
description	Investigation of spatial organization and relationships of biomolecules in cellular nanoenvironments is necessary to understand essential biological processes, but methodologically challenging. Here, the authors report cellular macromolecules-tethered DNA walking indexing (Cell-TALKING) to probe the nanoenvironments of DNA modifications around histone post-translational modifications, and explore the nanoenvironments in different cancer cell lines and clinical specimens.
format	article
author	Feng Chen Min Bai Xiaowen Cao Jing Xue Yue Zhao Na Wu Lei Wang Dexin Zhang Yongxi Zhao
author_facet	Feng Chen Min Bai Xiaowen Cao Jing Xue Yue Zhao Na Wu Lei Wang Dexin Zhang Yongxi Zhao
author_sort	Feng Chen
title	Cellular macromolecules-tethered DNA walking indexing to explore nanoenvironments of chromatin modifications
title_short	Cellular macromolecules-tethered DNA walking indexing to explore nanoenvironments of chromatin modifications
title_full	Cellular macromolecules-tethered DNA walking indexing to explore nanoenvironments of chromatin modifications
title_fullStr	Cellular macromolecules-tethered DNA walking indexing to explore nanoenvironments of chromatin modifications
title_full_unstemmed	Cellular macromolecules-tethered DNA walking indexing to explore nanoenvironments of chromatin modifications
title_sort	cellular macromolecules-tethered dna walking indexing to explore nanoenvironments of chromatin modifications
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1952b4348f4f496eb3d2dfe01f4ec6b8
work_keys_str_mv	AT fengchen cellularmacromoleculestethereddnawalkingindexingtoexplorenanoenvironmentsofchromatinmodifications AT minbai cellularmacromoleculestethereddnawalkingindexingtoexplorenanoenvironmentsofchromatinmodifications AT xiaowencao cellularmacromoleculestethereddnawalkingindexingtoexplorenanoenvironmentsofchromatinmodifications AT jingxue cellularmacromoleculestethereddnawalkingindexingtoexplorenanoenvironmentsofchromatinmodifications AT yuezhao cellularmacromoleculestethereddnawalkingindexingtoexplorenanoenvironmentsofchromatinmodifications AT nawu cellularmacromoleculestethereddnawalkingindexingtoexplorenanoenvironmentsofchromatinmodifications AT leiwang cellularmacromoleculestethereddnawalkingindexingtoexplorenanoenvironmentsofchromatinmodifications AT dexinzhang cellularmacromoleculestethereddnawalkingindexingtoexplorenanoenvironmentsofchromatinmodifications AT yongxizhao cellularmacromoleculestethereddnawalkingindexingtoexplorenanoenvironmentsofchromatinmodifications
_version_	1718378259699204096

Cellular macromolecules-tethered DNA walking indexing to explore nanoenvironments of chromatin modifications

Ejemplares similares