A molecular switch orchestrates enzyme specificity and secretory granule morphology

A molecular switch orchestrates enzyme specificity and secretory granule morphology

Regulated secretion is an essential process that requires packing and maturation of cargo proteins in membranous secretory granules. Here, authors identify a gene, pgant9, that influences the glycosylation status of the secretory cargo as well as the structure of secretory granules within the Drosop...

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Autores principales: Suena Ji, Nadine L. Samara, Leslie Revoredo, Liping Zhang, Duy T. Tran, Kayla Muirhead, Lawrence A. Tabak, Kelly G. Ten Hagen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/1955994d66254a509ac60c07ad959d67
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spelling oai:doaj.org-article:1955994d66254a509ac60c07ad959d672021-12-02T14:40:45ZA molecular switch orchestrates enzyme specificity and secretory granule morphology10.1038/s41467-018-05978-92041-1723https://doaj.org/article/1955994d66254a509ac60c07ad959d672018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05978-9https://doaj.org/toc/2041-1723Regulated secretion is an essential process that requires packing and maturation of cargo proteins in membranous secretory granules. Here, authors identify a gene, pgant9, that influences the glycosylation status of the secretory cargo as well as the structure of secretory granules within the Drosophila salivary gland.Suena JiNadine L. SamaraLeslie RevoredoLiping ZhangDuy T. TranKayla MuirheadLawrence A. TabakKelly G. Ten HagenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Suena Ji
Nadine L. Samara
Leslie Revoredo
Liping Zhang
Duy T. Tran
Kayla Muirhead
Lawrence A. Tabak
Kelly G. Ten Hagen
A molecular switch orchestrates enzyme specificity and secretory granule morphology
description Regulated secretion is an essential process that requires packing and maturation of cargo proteins in membranous secretory granules. Here, authors identify a gene, pgant9, that influences the glycosylation status of the secretory cargo as well as the structure of secretory granules within the Drosophila salivary gland.
format article
author Suena Ji
Nadine L. Samara
Leslie Revoredo
Liping Zhang
Duy T. Tran
Kayla Muirhead
Lawrence A. Tabak
Kelly G. Ten Hagen
author_facet Suena Ji
Nadine L. Samara
Leslie Revoredo
Liping Zhang
Duy T. Tran
Kayla Muirhead
Lawrence A. Tabak
Kelly G. Ten Hagen
author_sort Suena Ji
title A molecular switch orchestrates enzyme specificity and secretory granule morphology
title_short A molecular switch orchestrates enzyme specificity and secretory granule morphology
title_full A molecular switch orchestrates enzyme specificity and secretory granule morphology
title_fullStr A molecular switch orchestrates enzyme specificity and secretory granule morphology
title_full_unstemmed A molecular switch orchestrates enzyme specificity and secretory granule morphology
title_sort molecular switch orchestrates enzyme specificity and secretory granule morphology
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/1955994d66254a509ac60c07ad959d67
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