Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection
Dopamine (DA) is an important neurotransmitter in the kidney, cardiovascular system, and central nervous system, which abnormality is associated with many diseases. In this work, we synthesized a functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as the bio...
Guardado en:
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Taylor & Francis Group
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/195c368a631848399795537d9ee9cf87 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | Dopamine (DA) is an important neurotransmitter in the kidney, cardiovascular system, and central nervous system, which abnormality is associated with many diseases. In this work, we synthesized a functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as the biosensing material to detect DA. The SEM, EDS, and TEM characterizations indicated the success of the functionalization process with MWCNT as the base material. The values of the linear range, the limit of detection (LOD), and the selectivity of the nanocomposite were all obtained from the Differential Pulse Voltammetry (DPV) measurements. The obtained LOD value was 0.2778 µM in the linear range of 0–8 µM, which is lower than the required concentration value for detecting DA in human urine (0.3–3 µM). The biosensor’s high selectivity on DA with the presence of other human-related biofluids was also reported. These results show that f-MWCNT/AgNP nanocomposites are a promising biosensor material for the detection of DA. |
|---|