Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection

Dopamine (DA) is an important neurotransmitter in the kidney, cardiovascular system, and central nervous system, which abnormality is associated with many diseases. In this work, we synthesized a functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as the bio...

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Autores principales: Isa Anshori, Lavita Nuraviana Rizalputri, Raih Rona Althof, Steven Sean Surjadi, Suksmandhira Harimurti, Gilang Gumilar, Brian Yuliarto, Murni Handayani
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Publicado: Taylor & Francis Group 2021
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spelling oai:doaj.org-article:195c368a631848399795537d9ee9cf872021-12-02T16:25:31ZFunctionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection2055-033210.1080/20550324.2021.1948242https://doaj.org/article/195c368a631848399795537d9ee9cf872021-01-01T00:00:00Zhttp://dx.doi.org/10.1080/20550324.2021.1948242https://doaj.org/toc/2055-0332Dopamine (DA) is an important neurotransmitter in the kidney, cardiovascular system, and central nervous system, which abnormality is associated with many diseases. In this work, we synthesized a functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as the biosensing material to detect DA. The SEM, EDS, and TEM characterizations indicated the success of the functionalization process with MWCNT as the base material. The values of the linear range, the limit of detection (LOD), and the selectivity of the nanocomposite were all obtained from the Differential Pulse Voltammetry (DPV) measurements. The obtained LOD value was 0.2778 µM in the linear range of 0–8 µM, which is lower than the required concentration value for detecting DA in human urine (0.3–3 µM). The biosensor’s high selectivity on DA with the presence of other human-related biofluids was also reported. These results show that f-MWCNT/AgNP nanocomposites are a promising biosensor material for the detection of DA.Isa AnshoriLavita Nuraviana RizalputriRaih Rona AlthofSteven Sean SurjadiSuksmandhira HarimurtiGilang GumilarBrian YuliartoMurni HandayaniTaylor & Francis Grouparticledopaminemulti-walled carbon nanotubesilver nanoparticleelectrochemical biosensornon-enzymaticMaterials of engineering and construction. Mechanics of materialsTA401-492Polymers and polymer manufactureTP1080-1185ENNanocomposites, Vol 7, Iss 1, Pp 97-108 (2021)
institution DOAJ
collection DOAJ
language EN
topic dopamine
multi-walled carbon nanotube
silver nanoparticle
electrochemical biosensor
non-enzymatic
Materials of engineering and construction. Mechanics of materials
TA401-492
Polymers and polymer manufacture
TP1080-1185
spellingShingle dopamine
multi-walled carbon nanotube
silver nanoparticle
electrochemical biosensor
non-enzymatic
Materials of engineering and construction. Mechanics of materials
TA401-492
Polymers and polymer manufacture
TP1080-1185
Isa Anshori
Lavita Nuraviana Rizalputri
Raih Rona Althof
Steven Sean Surjadi
Suksmandhira Harimurti
Gilang Gumilar
Brian Yuliarto
Murni Handayani
Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection
description Dopamine (DA) is an important neurotransmitter in the kidney, cardiovascular system, and central nervous system, which abnormality is associated with many diseases. In this work, we synthesized a functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as the biosensing material to detect DA. The SEM, EDS, and TEM characterizations indicated the success of the functionalization process with MWCNT as the base material. The values of the linear range, the limit of detection (LOD), and the selectivity of the nanocomposite were all obtained from the Differential Pulse Voltammetry (DPV) measurements. The obtained LOD value was 0.2778 µM in the linear range of 0–8 µM, which is lower than the required concentration value for detecting DA in human urine (0.3–3 µM). The biosensor’s high selectivity on DA with the presence of other human-related biofluids was also reported. These results show that f-MWCNT/AgNP nanocomposites are a promising biosensor material for the detection of DA.
format article
author Isa Anshori
Lavita Nuraviana Rizalputri
Raih Rona Althof
Steven Sean Surjadi
Suksmandhira Harimurti
Gilang Gumilar
Brian Yuliarto
Murni Handayani
author_facet Isa Anshori
Lavita Nuraviana Rizalputri
Raih Rona Althof
Steven Sean Surjadi
Suksmandhira Harimurti
Gilang Gumilar
Brian Yuliarto
Murni Handayani
author_sort Isa Anshori
title Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection
title_short Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection
title_full Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection
title_fullStr Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection
title_full_unstemmed Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection
title_sort functionalized multi-walled carbon nanotube/silver nanoparticle (f-mwcnt/agnp) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection
publisher Taylor & Francis Group
publishDate 2021
url https://doaj.org/article/195c368a631848399795537d9ee9cf87
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