Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection
Dopamine (DA) is an important neurotransmitter in the kidney, cardiovascular system, and central nervous system, which abnormality is associated with many diseases. In this work, we synthesized a functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as the bio...
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2021
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oai:doaj.org-article:195c368a631848399795537d9ee9cf872021-12-02T16:25:31ZFunctionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection2055-033210.1080/20550324.2021.1948242https://doaj.org/article/195c368a631848399795537d9ee9cf872021-01-01T00:00:00Zhttp://dx.doi.org/10.1080/20550324.2021.1948242https://doaj.org/toc/2055-0332Dopamine (DA) is an important neurotransmitter in the kidney, cardiovascular system, and central nervous system, which abnormality is associated with many diseases. In this work, we synthesized a functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as the biosensing material to detect DA. The SEM, EDS, and TEM characterizations indicated the success of the functionalization process with MWCNT as the base material. The values of the linear range, the limit of detection (LOD), and the selectivity of the nanocomposite were all obtained from the Differential Pulse Voltammetry (DPV) measurements. The obtained LOD value was 0.2778 µM in the linear range of 0–8 µM, which is lower than the required concentration value for detecting DA in human urine (0.3–3 µM). The biosensor’s high selectivity on DA with the presence of other human-related biofluids was also reported. These results show that f-MWCNT/AgNP nanocomposites are a promising biosensor material for the detection of DA.Isa AnshoriLavita Nuraviana RizalputriRaih Rona AlthofSteven Sean SurjadiSuksmandhira HarimurtiGilang GumilarBrian YuliartoMurni HandayaniTaylor & Francis Grouparticledopaminemulti-walled carbon nanotubesilver nanoparticleelectrochemical biosensornon-enzymaticMaterials of engineering and construction. Mechanics of materialsTA401-492Polymers and polymer manufactureTP1080-1185ENNanocomposites, Vol 7, Iss 1, Pp 97-108 (2021) |
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DOAJ |
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dopamine multi-walled carbon nanotube silver nanoparticle electrochemical biosensor non-enzymatic Materials of engineering and construction. Mechanics of materials TA401-492 Polymers and polymer manufacture TP1080-1185 |
spellingShingle |
dopamine multi-walled carbon nanotube silver nanoparticle electrochemical biosensor non-enzymatic Materials of engineering and construction. Mechanics of materials TA401-492 Polymers and polymer manufacture TP1080-1185 Isa Anshori Lavita Nuraviana Rizalputri Raih Rona Althof Steven Sean Surjadi Suksmandhira Harimurti Gilang Gumilar Brian Yuliarto Murni Handayani Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
description |
Dopamine (DA) is an important neurotransmitter in the kidney, cardiovascular system, and central nervous system, which abnormality is associated with many diseases. In this work, we synthesized a functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as the biosensing material to detect DA. The SEM, EDS, and TEM characterizations indicated the success of the functionalization process with MWCNT as the base material. The values of the linear range, the limit of detection (LOD), and the selectivity of the nanocomposite were all obtained from the Differential Pulse Voltammetry (DPV) measurements. The obtained LOD value was 0.2778 µM in the linear range of 0–8 µM, which is lower than the required concentration value for detecting DA in human urine (0.3–3 µM). The biosensor’s high selectivity on DA with the presence of other human-related biofluids was also reported. These results show that f-MWCNT/AgNP nanocomposites are a promising biosensor material for the detection of DA. |
format |
article |
author |
Isa Anshori Lavita Nuraviana Rizalputri Raih Rona Althof Steven Sean Surjadi Suksmandhira Harimurti Gilang Gumilar Brian Yuliarto Murni Handayani |
author_facet |
Isa Anshori Lavita Nuraviana Rizalputri Raih Rona Althof Steven Sean Surjadi Suksmandhira Harimurti Gilang Gumilar Brian Yuliarto Murni Handayani |
author_sort |
Isa Anshori |
title |
Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
title_short |
Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
title_full |
Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
title_fullStr |
Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
title_full_unstemmed |
Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
title_sort |
functionalized multi-walled carbon nanotube/silver nanoparticle (f-mwcnt/agnp) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection |
publisher |
Taylor & Francis Group |
publishDate |
2021 |
url |
https://doaj.org/article/195c368a631848399795537d9ee9cf87 |
work_keys_str_mv |
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