Primary ectocervical epithelial cells display lower permissivity to Chlamydia trachomatis than HeLa cells and a globally higher pro-inflammatory profile

Primary ectocervical epithelial cells display lower permissivity to Chlamydia trachomatis than HeLa cells and a globally higher pro-inflammatory profile

Abstract The tumoral origin and extensive passaging of HeLa cells, a most commonly used cervical epithelial cell line, raise concerns on their suitability to study the cell responses to infection. The present study was designed to isolate primary epithelial cells from human ectocervix explants and c...

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Autores principales: Chongfa Tang, Chang Liu, Benoit Maffei, Béatrice Niragire, Henri Cohen, Aminata Kane, Anne-Claire Donnadieu, Yael Levy-Zauberman, Thomas Vernay, Juliette Hugueny, Etienne Vincens, Christine Louis-Sylvestre, Agathe Subtil, Yongzheng Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/195d3f7cbfb64e4db7b039c292bd24fa
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