Hyperstretching DNA

The mechanics and structural transitions of DNA are important to many essential processes inside living cells. Here the authors combine theory and single-molecule experiments to show that intercalator binding stabilises a new structural state of DNA: hyperstretched DNA.

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Autores principales:	Koen Schakenraad, Andreas S. Biebricher, Maarten Sebregts, Brian ten Bensel, Erwin J. G. Peterman, Gijs J. L. Wuite, Iddo Heller, Cornelis Storm, Paul van der Schoot
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/19651989c29f4b8187a2b287c64a0905
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id	oai:doaj.org-article:19651989c29f4b8187a2b287c64a0905
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spelling	oai:doaj.org-article:19651989c29f4b8187a2b287c64a09052021-12-02T15:38:47ZHyperstretching DNA10.1038/s41467-017-02396-12041-1723https://doaj.org/article/19651989c29f4b8187a2b287c64a09052017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02396-1https://doaj.org/toc/2041-1723The mechanics and structural transitions of DNA are important to many essential processes inside living cells. Here the authors combine theory and single-molecule experiments to show that intercalator binding stabilises a new structural state of DNA: hyperstretched DNA.Koen SchakenraadAndreas S. BiebricherMaarten SebregtsBrian ten BenselErwin J. G. PetermanGijs J. L. WuiteIddo HellerCornelis StormPaul van der SchootNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Koen Schakenraad Andreas S. Biebricher Maarten Sebregts Brian ten Bensel Erwin J. G. Peterman Gijs J. L. Wuite Iddo Heller Cornelis Storm Paul van der Schoot Hyperstretching DNA
description	The mechanics and structural transitions of DNA are important to many essential processes inside living cells. Here the authors combine theory and single-molecule experiments to show that intercalator binding stabilises a new structural state of DNA: hyperstretched DNA.
format	article
author	Koen Schakenraad Andreas S. Biebricher Maarten Sebregts Brian ten Bensel Erwin J. G. Peterman Gijs J. L. Wuite Iddo Heller Cornelis Storm Paul van der Schoot
author_facet	Koen Schakenraad Andreas S. Biebricher Maarten Sebregts Brian ten Bensel Erwin J. G. Peterman Gijs J. L. Wuite Iddo Heller Cornelis Storm Paul van der Schoot
author_sort	Koen Schakenraad
title	Hyperstretching DNA
title_short	Hyperstretching DNA
title_full	Hyperstretching DNA
title_fullStr	Hyperstretching DNA
title_full_unstemmed	Hyperstretching DNA
title_sort	hyperstretching dna
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/19651989c29f4b8187a2b287c64a0905
work_keys_str_mv	AT koenschakenraad hyperstretchingdna AT andreassbiebricher hyperstretchingdna AT maartensebregts hyperstretchingdna AT briantenbensel hyperstretchingdna AT erwinjgpeterman hyperstretchingdna AT gijsjlwuite hyperstretchingdna AT iddoheller hyperstretchingdna AT cornelisstorm hyperstretchingdna AT paulvanderschoot hyperstretchingdna
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Hyperstretching DNA

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