Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation.

Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation.

Mutated tyrosine kinases are associated with a number of different haematological malignancies including myeloproliferative disorders, lymphoma and acute myeloid leukaemia. The potential commonalities in the action of six of these leukemogenic proteins on nuclear proteins were investigated using sys...

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Autores principales: Andrew Pierce, Andrew Williamson, Ewa Jaworska, John R Griffiths, Sam Taylor, Michael Walker, Mark Aspinall-O'Dea, Elaine Spooncer, Richard D Unwin, Toryn Poolman, David Ray, Anthony D Whetton
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/196965d7fc1a435eaf81238cb16e8818
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