Progesterone prevents epithelial-mesenchymal transition of ovine amniotic epithelial cells and enhances their immunomodulatory properties
Abstract The in vitro expansion is detrimental to therapeutic applications of amniotic epithelial cells (AEC), an emerging source of fetal stem cells. This study provides molecular evidences of progesterone (P4) role in preventing epithelial-mesenchymal transition (EMT) in ovine AEC (oAEC). oAEC amp...
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Autores principales: | Angelo Canciello, Valentina Russo, Paolo Berardinelli, Nicola Bernabò, Aurelio Muttini, Mauro Mattioli, Barbara Barboni |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/1979f71eb3984872b82d9e36e5717311 |
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