COMPARISON OF EFFECT OF PRIMARY PERCUTANEOUS CORONARY INTERVENTION WITH STREPTOKINASE IN ACUTE ST ELEVATION MYOCARDIAL INFARCTION (STEMI) ON LEFT VENTRICULAR FUNCTION AFTER 3 MONTHS

Objective: To assess the left ventricular function three months after the primary percutaneous coronary intervention versus Streptokinase in ST elevation myocardial infarction. Study Design: Prospective comparative study. Place and Duration of Study: Cardiac Catheterization Lab, in-patients an...

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Autores principales:	Saleha Abbas, Abdul Hameed Siddiqui, Ammar Cheema, Ayesha Abbas, Sadaf Khan, Anum Fatima Janjua, Farhan Tuyyab
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2020
Materias:	hyperlipidemia primary percutaneous coronary intervention streptokinase st elevation myocardial infarction Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/1983fc682e204bc5bf5d50991339de73
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spelling	oai:doaj.org-article:1983fc682e204bc5bf5d50991339de732021-12-02T17:19:04ZCOMPARISON OF EFFECT OF PRIMARY PERCUTANEOUS CORONARY INTERVENTION WITH STREPTOKINASE IN ACUTE ST ELEVATION MYOCARDIAL INFARCTION (STEMI) ON LEFT VENTRICULAR FUNCTION AFTER 3 MONTHSdoi.org/10.51253/pafmj.v70iSuppl-4.60440030-96482411-8842https://doaj.org/article/1983fc682e204bc5bf5d50991339de732020-12-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/6044https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To assess the left ventricular function three months after the primary percutaneous coronary intervention versus Streptokinase in ST elevation myocardial infarction. Study Design: Prospective comparative study. Place and Duration of Study: Cardiac Catheterization Lab, in-patients and out patients departments of Armed Forces Institute of Cardiology and National Institute of Heart Diseases, Rawalpindi from Jun 2018 to Jun 2019. Methodology: Patients included in the study were with first acute MI treated with primary PCI/SK, having systolic blood pressure >90 mmhg, pre-infarction EF >40% and with no previous history of coronary artery bypass grafting or angioplasty. All patients undergoing primary percutaneous coronary intervention/Streptokinase injection were assessed for left ventricular function at day one by transthoracic echocardiography and then three months later by transthoracic echocardiography. Two-dimensional echocardiography was being performed immediately after primary percutaneous coronary intervention on day one and at three months follow-up. Results: There were 80 patients recruited in the study. Mean age of the patients was 55.5 ± 11.6 years with range 36-81 years. Sixty nine (86.3%) patients were male while 11 (13.48%) were female patients. Most common comorbid was smoking 37 (46.3%) followed by diabetes mellitus 25 (31.3%). Most common culprit artery was left anterior descending 38 (47.5%) followed by left circumflex 15 (18.8%) and then right coronary artery 14 (17.5%). Independent sample t-test was applied to find out the statistical significance between two groups (Streptokinase group vs PPCI group). Ejection fraction of the patients was checked at the time of discharge and after three months follow-up and result showed the statistical significance with p-value <0.05. Conclusion: Based on this comparative analysis of improvement of left ventricular function between streptokinase and primary percutaneous coronary intervention, we concluded that after three months satisfactory ejection fraction is seen in patients treated with primary percutaneous coronary intervention as compared to patients treated with streptokinase.Saleha AbbasAbdul Hameed SiddiquiAmmar CheemaAyesha AbbasSadaf KhanAnum Fatima JanjuaFarhan TuyyabArmy Medical College Rawalpindiarticlehyperlipidemiaprimary percutaneous coronary interventionstreptokinasest elevation myocardial infarctionMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 4, Pp 860-864 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	hyperlipidemia primary percutaneous coronary intervention streptokinase st elevation myocardial infarction Medicine R Medicine (General) R5-920
spellingShingle	hyperlipidemia primary percutaneous coronary intervention streptokinase st elevation myocardial infarction Medicine R Medicine (General) R5-920 Saleha Abbas Abdul Hameed Siddiqui Ammar Cheema Ayesha Abbas Sadaf Khan Anum Fatima Janjua Farhan Tuyyab COMPARISON OF EFFECT OF PRIMARY PERCUTANEOUS CORONARY INTERVENTION WITH STREPTOKINASE IN ACUTE ST ELEVATION MYOCARDIAL INFARCTION (STEMI) ON LEFT VENTRICULAR FUNCTION AFTER 3 MONTHS
description	Objective: To assess the left ventricular function three months after the primary percutaneous coronary intervention versus Streptokinase in ST elevation myocardial infarction. Study Design: Prospective comparative study. Place and Duration of Study: Cardiac Catheterization Lab, in-patients and out patients departments of Armed Forces Institute of Cardiology and National Institute of Heart Diseases, Rawalpindi from Jun 2018 to Jun 2019. Methodology: Patients included in the study were with first acute MI treated with primary PCI/SK, having systolic blood pressure >90 mmhg, pre-infarction EF >40% and with no previous history of coronary artery bypass grafting or angioplasty. All patients undergoing primary percutaneous coronary intervention/Streptokinase injection were assessed for left ventricular function at day one by transthoracic echocardiography and then three months later by transthoracic echocardiography. Two-dimensional echocardiography was being performed immediately after primary percutaneous coronary intervention on day one and at three months follow-up. Results: There were 80 patients recruited in the study. Mean age of the patients was 55.5 ± 11.6 years with range 36-81 years. Sixty nine (86.3%) patients were male while 11 (13.48%) were female patients. Most common comorbid was smoking 37 (46.3%) followed by diabetes mellitus 25 (31.3%). Most common culprit artery was left anterior descending 38 (47.5%) followed by left circumflex 15 (18.8%) and then right coronary artery 14 (17.5%). Independent sample t-test was applied to find out the statistical significance between two groups (Streptokinase group vs PPCI group). Ejection fraction of the patients was checked at the time of discharge and after three months follow-up and result showed the statistical significance with p-value <0.05. Conclusion: Based on this comparative analysis of improvement of left ventricular function between streptokinase and primary percutaneous coronary intervention, we concluded that after three months satisfactory ejection fraction is seen in patients treated with primary percutaneous coronary intervention as compared to patients treated with streptokinase.
format	article
author	Saleha Abbas Abdul Hameed Siddiqui Ammar Cheema Ayesha Abbas Sadaf Khan Anum Fatima Janjua Farhan Tuyyab
author_facet	Saleha Abbas Abdul Hameed Siddiqui Ammar Cheema Ayesha Abbas Sadaf Khan Anum Fatima Janjua Farhan Tuyyab
author_sort	Saleha Abbas
title	COMPARISON OF EFFECT OF PRIMARY PERCUTANEOUS CORONARY INTERVENTION WITH STREPTOKINASE IN ACUTE ST ELEVATION MYOCARDIAL INFARCTION (STEMI) ON LEFT VENTRICULAR FUNCTION AFTER 3 MONTHS
title_short	COMPARISON OF EFFECT OF PRIMARY PERCUTANEOUS CORONARY INTERVENTION WITH STREPTOKINASE IN ACUTE ST ELEVATION MYOCARDIAL INFARCTION (STEMI) ON LEFT VENTRICULAR FUNCTION AFTER 3 MONTHS
title_full	COMPARISON OF EFFECT OF PRIMARY PERCUTANEOUS CORONARY INTERVENTION WITH STREPTOKINASE IN ACUTE ST ELEVATION MYOCARDIAL INFARCTION (STEMI) ON LEFT VENTRICULAR FUNCTION AFTER 3 MONTHS
title_fullStr	COMPARISON OF EFFECT OF PRIMARY PERCUTANEOUS CORONARY INTERVENTION WITH STREPTOKINASE IN ACUTE ST ELEVATION MYOCARDIAL INFARCTION (STEMI) ON LEFT VENTRICULAR FUNCTION AFTER 3 MONTHS
title_full_unstemmed	COMPARISON OF EFFECT OF PRIMARY PERCUTANEOUS CORONARY INTERVENTION WITH STREPTOKINASE IN ACUTE ST ELEVATION MYOCARDIAL INFARCTION (STEMI) ON LEFT VENTRICULAR FUNCTION AFTER 3 MONTHS
title_sort	comparison of effect of primary percutaneous coronary intervention with streptokinase in acute st elevation myocardial infarction (stemi) on left ventricular function after 3 months
publisher	Army Medical College Rawalpindi
publishDate	2020
url	https://doaj.org/article/1983fc682e204bc5bf5d50991339de73
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COMPARISON OF EFFECT OF PRIMARY PERCUTANEOUS CORONARY INTERVENTION WITH STREPTOKINASE IN ACUTE ST ELEVATION MYOCARDIAL INFARCTION (STEMI) ON LEFT VENTRICULAR FUNCTION AFTER 3 MONTHS

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