Two or More Levels Anterior Cervical Discectomy and Fusion (ACDF) Using Stand-Alone PEEK Cages Filled With Bone Graft Substitute

Background Data: Anterior cervical discectomy and fusion (ACDF) has become a standard and a highly successful procedure for degenerative cervical disc disease associated with radiculopathy or myelopathy. In addition to graft complication, multilevel cervical discectomy is often combined with plate f...

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Autores principales:	Mohamad El-Meshtawy, Belal Elnady, Khaled Hassan, Hamdan Ahmad, Mohamad Hassan, Mahmoud Fouad, Amr Abo El-Fadl
Formato:	article
Lenguaje:	EN
Publicado:	Egyptian Spine Association 2013
Materias:	cervical spine Multi-level cervical disc disease ACDF PEEK cage Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/1991aa2e5625473b8d3fe36ec083b6f4
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spelling	oai:doaj.org-article:1991aa2e5625473b8d3fe36ec083b6f42021-12-02T03:45:17ZTwo or More Levels Anterior Cervical Discectomy and Fusion (ACDF) Using Stand-Alone PEEK Cages Filled With Bone Graft SubstituteDOI:10.21608/ESJ.2013.38172314-89502314-8969https://doaj.org/article/1991aa2e5625473b8d3fe36ec083b6f42013-04-01T00:00:00Zhttp://esj.journals.ekb.eg/article_3817.htmlhttps://doaj.org/toc/2314-8950https://doaj.org/toc/2314-8969Background Data: Anterior cervical discectomy and fusion (ACDF) has become a standard and a highly successful procedure for degenerative cervical disc disease associated with radiculopathy or myelopathy. In addition to graft complication, multilevel cervical discectomy is often combined with plate fixation to maintain the spinal curvature, and increasing the graft fusion rate but this also may carry risk of complications. Study Design: Prospective descriptive clinical case study Purpose: To evaluate the safety and efficacy of standalone PEEK cages filled with bone graft substitute in treatment of multi-level cervical disc disease. Patients and Methods: Ninety one patients underwent multiple levels ACDF for a total of 239 levels. Mean follow-up was 24 months. Clinical outcomes were evaluated using Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI); cervical lordosis and cervical fusion status was assessed on X-ray. Statistical analysis was performed using a dependent t-test using SPSS V.12.0 (P<0.05). Results: The fusion rate was 97.9% (234 out of total 239 levels operated). Clinically, the mean ODI scores were 50.49 (Range, 30 to 69) preoperatively and 16.89 (Range, 0 to 38) postoperatively (P=0.000). All patient have significant pain reduction with mean VAS scores decreases from 6.52 (Range, 4 to 9) preoperative to 1.87 (Range, 0 to 5) postoperatively (P=0.000). Cervical lordosis was preserved and neurological status was improved. No cage migration or cage breakage happened. Conclusion: ACDF using standalone PEEK cages filled with Calcium triphosphate bone graft substitute is a safe and efficient method for treatment of multiple levels cervical disc disease. It preserves cervical lordosis and obviates the complications related to iliac crest grafting and screw-plate fixation. (2013ESJ045)Mohamad El-Meshtawy Belal ElnadyKhaled Hassan Hamdan AhmadMohamad Hassan Mahmoud Fouad Amr Abo El-FadlEgyptian Spine Associationarticlecervical spineMulti-level cervical disc diseaseACDFPEEK cageNeurology. Diseases of the nervous systemRC346-429ENEgyptian Spine Journal, Vol 6, Iss 1, Pp 30-37 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	cervical spine Multi-level cervical disc disease ACDF PEEK cage Neurology. Diseases of the nervous system RC346-429
spellingShingle	cervical spine Multi-level cervical disc disease ACDF PEEK cage Neurology. Diseases of the nervous system RC346-429 Mohamad El-Meshtawy Belal Elnady Khaled Hassan Hamdan Ahmad Mohamad Hassan Mahmoud Fouad Amr Abo El-Fadl Two or More Levels Anterior Cervical Discectomy and Fusion (ACDF) Using Stand-Alone PEEK Cages Filled With Bone Graft Substitute
description	Background Data: Anterior cervical discectomy and fusion (ACDF) has become a standard and a highly successful procedure for degenerative cervical disc disease associated with radiculopathy or myelopathy. In addition to graft complication, multilevel cervical discectomy is often combined with plate fixation to maintain the spinal curvature, and increasing the graft fusion rate but this also may carry risk of complications. Study Design: Prospective descriptive clinical case study Purpose: To evaluate the safety and efficacy of standalone PEEK cages filled with bone graft substitute in treatment of multi-level cervical disc disease. Patients and Methods: Ninety one patients underwent multiple levels ACDF for a total of 239 levels. Mean follow-up was 24 months. Clinical outcomes were evaluated using Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI); cervical lordosis and cervical fusion status was assessed on X-ray. Statistical analysis was performed using a dependent t-test using SPSS V.12.0 (P<0.05). Results: The fusion rate was 97.9% (234 out of total 239 levels operated). Clinically, the mean ODI scores were 50.49 (Range, 30 to 69) preoperatively and 16.89 (Range, 0 to 38) postoperatively (P=0.000). All patient have significant pain reduction with mean VAS scores decreases from 6.52 (Range, 4 to 9) preoperative to 1.87 (Range, 0 to 5) postoperatively (P=0.000). Cervical lordosis was preserved and neurological status was improved. No cage migration or cage breakage happened. Conclusion: ACDF using standalone PEEK cages filled with Calcium triphosphate bone graft substitute is a safe and efficient method for treatment of multiple levels cervical disc disease. It preserves cervical lordosis and obviates the complications related to iliac crest grafting and screw-plate fixation. (2013ESJ045)
format	article
author	Mohamad El-Meshtawy Belal Elnady Khaled Hassan Hamdan Ahmad Mohamad Hassan Mahmoud Fouad Amr Abo El-Fadl
author_facet	Mohamad El-Meshtawy Belal Elnady Khaled Hassan Hamdan Ahmad Mohamad Hassan Mahmoud Fouad Amr Abo El-Fadl
author_sort	Mohamad El-Meshtawy
title	Two or More Levels Anterior Cervical Discectomy and Fusion (ACDF) Using Stand-Alone PEEK Cages Filled With Bone Graft Substitute
title_short	Two or More Levels Anterior Cervical Discectomy and Fusion (ACDF) Using Stand-Alone PEEK Cages Filled With Bone Graft Substitute
title_full	Two or More Levels Anterior Cervical Discectomy and Fusion (ACDF) Using Stand-Alone PEEK Cages Filled With Bone Graft Substitute
title_fullStr	Two or More Levels Anterior Cervical Discectomy and Fusion (ACDF) Using Stand-Alone PEEK Cages Filled With Bone Graft Substitute
title_full_unstemmed	Two or More Levels Anterior Cervical Discectomy and Fusion (ACDF) Using Stand-Alone PEEK Cages Filled With Bone Graft Substitute
title_sort	two or more levels anterior cervical discectomy and fusion (acdf) using stand-alone peek cages filled with bone graft substitute
publisher	Egyptian Spine Association
publishDate	2013
url	https://doaj.org/article/1991aa2e5625473b8d3fe36ec083b6f4
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Two or More Levels Anterior Cervical Discectomy and Fusion (ACDF) Using Stand-Alone PEEK Cages Filled With Bone Graft Substitute

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