Synthesis of New 1-Aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone Oxime Ether Derivatives and Investigation of Their Cytotoxic Effects

Synthesis of New 1-Aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone Oxime Ether Derivatives and Investigation of Their Cytotoxic Effects

In this study, 12 new 1-aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone oxime ether derivatives were designed and synthesized to investigate their cytotoxic effects. The in vitro cytotoxic activities of the compounds were evaluated against cervix, colon, breast, glioma, neuroblastoma, and lung cancer cell...

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Bibliographic Details
Main Authors: Mehmet Abdullah Alagöz, Arzu Karakurt, Ceylan Hepokur, Emine Şalva, Tijen Önkol, Mohammed M. Ghoneim, Mohamed A. Abdelgawad, Ahmed Khames, Hoon Kim, Bijo Mathew
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
3,5-dimethylpyrazole
oxime ether
cytotoxic activity
glioma
neuroblastoma
Chemical technology
TP1-1185
Chemistry
QD1-999
Online Access:https://doaj.org/article/19a099d881904d038975d9c51ac5960f
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https://doaj.org/article/19a099d881904d038975d9c51ac5960f

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