Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism
Aberrant gene expression in cancer coincides with drastic changes in metabolism. Here, the authors combined metabolome, transcriptome and proteome data in 54 cancer cell lines to uncover a genome-scale network of associations between transcriptional regulators and metabolites.
Guardado en:
Autores principales: | , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/19a0aeae043341178fd7a04d59da82b2 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:19a0aeae043341178fd7a04d59da82b2 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:19a0aeae043341178fd7a04d59da82b22021-12-02T14:38:38ZMetabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism10.1038/s41467-019-09695-92041-1723https://doaj.org/article/19a0aeae043341178fd7a04d59da82b22019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09695-9https://doaj.org/toc/2041-1723Aberrant gene expression in cancer coincides with drastic changes in metabolism. Here, the authors combined metabolome, transcriptome and proteome data in 54 cancer cell lines to uncover a genome-scale network of associations between transcriptional regulators and metabolites.Karin OrtmayrSébastien DubuisMattia ZampieriNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Karin Ortmayr Sébastien Dubuis Mattia Zampieri Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism |
description |
Aberrant gene expression in cancer coincides with drastic changes in metabolism. Here, the authors combined metabolome, transcriptome and proteome data in 54 cancer cell lines to uncover a genome-scale network of associations between transcriptional regulators and metabolites. |
format |
article |
author |
Karin Ortmayr Sébastien Dubuis Mattia Zampieri |
author_facet |
Karin Ortmayr Sébastien Dubuis Mattia Zampieri |
author_sort |
Karin Ortmayr |
title |
Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism |
title_short |
Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism |
title_full |
Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism |
title_fullStr |
Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism |
title_full_unstemmed |
Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism |
title_sort |
metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/19a0aeae043341178fd7a04d59da82b2 |
work_keys_str_mv |
AT karinortmayr metabolicprofilingofcancercellsrevealsgenomewidecrosstalkbetweentranscriptionalregulatorsandmetabolism AT sebastiendubuis metabolicprofilingofcancercellsrevealsgenomewidecrosstalkbetweentranscriptionalregulatorsandmetabolism AT mattiazampieri metabolicprofilingofcancercellsrevealsgenomewidecrosstalkbetweentranscriptionalregulatorsandmetabolism |
_version_ |
1718390877383032832 |