Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism

Aberrant gene expression in cancer coincides with drastic changes in metabolism. Here, the authors combined metabolome, transcriptome and proteome data in 54 cancer cell lines to uncover a genome-scale network of associations between transcriptional regulators and metabolites.

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Detalles Bibliográficos
Autores principales: Karin Ortmayr, Sébastien Dubuis, Mattia Zampieri
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
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Acceso en línea:https://doaj.org/article/19a0aeae043341178fd7a04d59da82b2
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