Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism

Aberrant gene expression in cancer coincides with drastic changes in metabolism. Here, the authors combined metabolome, transcriptome and proteome data in 54 cancer cell lines to uncover a genome-scale network of associations between transcriptional regulators and metabolites.

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Auteurs principaux: Karin Ortmayr, Sébastien Dubuis, Mattia Zampieri
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/19a0aeae043341178fd7a04d59da82b2
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