The molecular landscape of Asian breast cancers reveals clinically relevant population-specific differences

The molecular landscape of Asian breast cancers reveals clinically relevant population-specific differences

Molecular profiling of breast cancer in non-Caucasian populations remains underexplored. Here the authors report a high prevalence of HER2-subtypes and enriched immune score with improved survival and higher rates of TP53 somatic mutations with poorer survival in ER+ tumours in a Malaysian cohort.

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Detalles Bibliográficos
Autores principales: Jia-Wern Pan, Muhammad Mamduh Ahmad Zabidi, Pei-Sze Ng, Mei-Yee Meng, Siti Norhidayu Hasan, Bethan Sandey, Stephen-John Sammut, Cheng-Har Yip, Pathmanathan Rajadurai, Oscar M. Rueda, Carlos Caldas, Suet-Feung Chin, Soo-Hwang Teo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/19a345c9f0be4ab783dcad50c106ed15
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