Feedback regulation of apical progenitor fate by immature neurons through Wnt7–Celsr3–Fzd3 signalling

The switch from neurogenesis to gliogenesis in cortical development is only partially understood. Here the authors show that Wnt-Planar cell polarity signaling in immature cortical neurons activates Notch in neural progenitor cells, thereby tuning the timing of their fate decisions.

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Main Authors:	Wei Wang, Yves Jossin, Guoliang Chai, Wen-Hui Lien, Fadel Tissir, Andre M. Goffinet
Format:	article
Language:	EN
Published:	Nature Portfolio 2016
Subjects:	Science Q
Online Access:	https://doaj.org/article/19a7dc4cb6ac4f5c9efbff9cae5d14d6
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spelling	oai:doaj.org-article:19a7dc4cb6ac4f5c9efbff9cae5d14d62021-12-02T17:32:22ZFeedback regulation of apical progenitor fate by immature neurons through Wnt7–Celsr3–Fzd3 signalling10.1038/ncomms109362041-1723https://doaj.org/article/19a7dc4cb6ac4f5c9efbff9cae5d14d62016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10936https://doaj.org/toc/2041-1723The switch from neurogenesis to gliogenesis in cortical development is only partially understood. Here the authors show that Wnt-Planar cell polarity signaling in immature cortical neurons activates Notch in neural progenitor cells, thereby tuning the timing of their fate decisions.Wei WangYves JossinGuoliang ChaiWen-Hui LienFadel TissirAndre M. GoffinetNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wei Wang Yves Jossin Guoliang Chai Wen-Hui Lien Fadel Tissir Andre M. Goffinet Feedback regulation of apical progenitor fate by immature neurons through Wnt7–Celsr3–Fzd3 signalling
description	The switch from neurogenesis to gliogenesis in cortical development is only partially understood. Here the authors show that Wnt-Planar cell polarity signaling in immature cortical neurons activates Notch in neural progenitor cells, thereby tuning the timing of their fate decisions.
format	article
author	Wei Wang Yves Jossin Guoliang Chai Wen-Hui Lien Fadel Tissir Andre M. Goffinet
author_facet	Wei Wang Yves Jossin Guoliang Chai Wen-Hui Lien Fadel Tissir Andre M. Goffinet
author_sort	Wei Wang
title	Feedback regulation of apical progenitor fate by immature neurons through Wnt7–Celsr3–Fzd3 signalling
title_short	Feedback regulation of apical progenitor fate by immature neurons through Wnt7–Celsr3–Fzd3 signalling
title_full	Feedback regulation of apical progenitor fate by immature neurons through Wnt7–Celsr3–Fzd3 signalling
title_fullStr	Feedback regulation of apical progenitor fate by immature neurons through Wnt7–Celsr3–Fzd3 signalling
title_full_unstemmed	Feedback regulation of apical progenitor fate by immature neurons through Wnt7–Celsr3–Fzd3 signalling
title_sort	feedback regulation of apical progenitor fate by immature neurons through wnt7–celsr3–fzd3 signalling
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/19a7dc4cb6ac4f5c9efbff9cae5d14d6
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Feedback regulation of apical progenitor fate by immature neurons through Wnt7–Celsr3–Fzd3 signalling

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