Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure

Circadian variation of blood pressure, with higher values in the active period, is associated with the risk of fatal cardiovascular events. Here, we show the importance of renal TRPM6, a Magnesium-permeable cation channel, in raising blood pressure by stimulating renin secretion.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Yosuke Funato, Daisuke Yamazaki, Daisuke Okuzaki, Nobuhiko Yamamoto, Hiroaki Miki
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Q
Accès en ligne:https://doaj.org/article/19ab4e3777194204aa8e0dcab04a04d6
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
id oai:doaj.org-article:19ab4e3777194204aa8e0dcab04a04d6
record_format dspace
spelling oai:doaj.org-article:19ab4e3777194204aa8e0dcab04a04d62021-12-02T16:04:12ZImportance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure10.1038/s41467-021-24063-22041-1723https://doaj.org/article/19ab4e3777194204aa8e0dcab04a04d62021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24063-2https://doaj.org/toc/2041-1723Circadian variation of blood pressure, with higher values in the active period, is associated with the risk of fatal cardiovascular events. Here, we show the importance of renal TRPM6, a Magnesium-permeable cation channel, in raising blood pressure by stimulating renin secretion.Yosuke FunatoDaisuke YamazakiDaisuke OkuzakiNobuhiko YamamotoHiroaki MikiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yosuke Funato
Daisuke Yamazaki
Daisuke Okuzaki
Nobuhiko Yamamoto
Hiroaki Miki
Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure
description Circadian variation of blood pressure, with higher values in the active period, is associated with the risk of fatal cardiovascular events. Here, we show the importance of renal TRPM6, a Magnesium-permeable cation channel, in raising blood pressure by stimulating renin secretion.
format article
author Yosuke Funato
Daisuke Yamazaki
Daisuke Okuzaki
Nobuhiko Yamamoto
Hiroaki Miki
author_facet Yosuke Funato
Daisuke Yamazaki
Daisuke Okuzaki
Nobuhiko Yamamoto
Hiroaki Miki
author_sort Yosuke Funato
title Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure
title_short Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure
title_full Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure
title_fullStr Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure
title_full_unstemmed Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure
title_sort importance of the renal ion channel trpm6 in the circadian secretion of renin to raise blood pressure
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/19ab4e3777194204aa8e0dcab04a04d6
work_keys_str_mv AT yosukefunato importanceoftherenalionchanneltrpm6inthecircadiansecretionofrenintoraisebloodpressure
AT daisukeyamazaki importanceoftherenalionchanneltrpm6inthecircadiansecretionofrenintoraisebloodpressure
AT daisukeokuzaki importanceoftherenalionchanneltrpm6inthecircadiansecretionofrenintoraisebloodpressure
AT nobuhikoyamamoto importanceoftherenalionchanneltrpm6inthecircadiansecretionofrenintoraisebloodpressure
AT hiroakimiki importanceoftherenalionchanneltrpm6inthecircadiansecretionofrenintoraisebloodpressure
_version_ 1718385256552202240